DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CLIP1 and TBCB

DIOPT Version :9

Sequence 1:	NP_001376220.1	Gene:	CLIP1 / 6249	HGNCID:	10461	Length:	2148	Species:	Homo sapiens
Sequence 2:	NP_611425.1	Gene:	TBCB / 37244	FlyBaseID:	FBgn0034451	Length:	244	Species:	Drosophila melanogaster

Alignment Length:	109	Identity:	40/109 - (36%)
Similarity:	52/109 - (47%)	Gaps:	9/109 - (8%)

- Green bases have known domain annotations that are detailed below.

Human   185 ISNLTKTASESISNLSE-----AGSIKKGERELKIGDR--VLVGG--TKAGVVRFLGETDFAKGE 240
            |:.:.|...|.:....|     |..|:|......:|.|  |.|.|  |:.|.:|:.|..:...|.
  Fly   126 INRMGKYNDEEMQQAEEKKRLQAEEIQKRAELCVLGGRCEVTVPGNPTRRGTIRYNGPLEGKSGH 190

Human   241 WCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTKIGFP 284
            :.|||.|||||||:|:..|..||.|.|.||.|.....||...||
  Fly   191 FIGVEYDEPLGKNNGSFGGKAYFTCAPNYGGFVSPLSVTVGDFP 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CLIP1	NP_001376220.1	CAP_GLY	60..124	CDD:396049
		CAP_GLY	214..278	CDD:396049	29/67 (43%)
		SbcC	<335..835	CDD:223496
		Smc	612..1442	CDD:224117
		Smc	1176..1977	CDD:224117
		CLIP1_ZNF	2126..2142	CDD:406934
TBCB	NP_611425.1	Alp11_N	12..95	CDD:176384
TBCB	NP_611425.1	CAP_GLY	161..225	CDD:279625	29/63 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910