Protein Alignment RRM2 and RnrS

DIOPT Version :10

• Sequence 1: NP_001159403.1
• Gene: RRM2 / 6241
• HGNCID: 10452
• Length: 449
• Species: Homo sapiens
• Sequence 2: NP_525111.1
• Gene: RnrS / 36280
• FlyBaseID: FBgn0011704
• Length: 393
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 274/377 - (72%)
• Similarity: 307/377 - (81%)
• Gaps: 8/377 - (2%)

Human    80 SPLKGLSLVDKENTPPALS------GTRVLASKTARRIFQEPTEPKTKAAAP-GVEDEPLLRENP 137
            ||.|.: |.|..|....:|      |.....|.|...|.:.......|:..| ....||||||||
  Fly    18 SPSKKI-LTDSTNNVRKMSIGHEANGQLAKESSTVNGIGKSANSLMEKSVTPFDPSLEPLLRENP 81

Human   138 RRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVN 202
            ||||||||:|||||||||||||||||.||||||||:..|..||.:||:|||||||||||||||||
  Fly    82 RRFVIFPIQYHDIWQMYKKAEASFWTVEEVDLSKDLTDWHRLKDDERHFISHVLAFFAASDGIVN 146

Human   203 ENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKA 267
            ||||||||||||||||||||||||||||:||||||:||||||:||.:||:|||||||||.||:||
  Fly   147 ENLVERFSQEVQITEARCFYGFQIAMENVHSEMYSVLIDTYIRDPHQREYLFNAIETMPAVKRKA 211

Human   268 DWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDF 332
            ||||.||..|.|.:|||::||||||||||||||||||||||||||||||||||||||||||||||
  Fly   212 DWALSWISSKSANFGERIIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDF 276

Human   333 ACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGF 397
            |.|||:|||.:|..||:.|||.:||.|||||||:||||.||||||.||.||||||||||::|||.
  Fly   277 AVLMFQHLVQRPKRERIIEIIRDAVAIEQEFLTDALPVNLIGMNCDLMSQYIEFVADRLLVELGV 341

Human   398 SKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF 449
            .|::..:|||:|||.|||:||||||||:|||||||||:|:|.:|.|||||||
  Fly   342 GKIYNTKNPFNFMEMISLDGKTNFFEKKVGEYQRMGVVSNPLDNVFTLDADF 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RRM2	NP_001159403.1	PLN02492	130..449	CDD:215272	259/318 (81%)
RnrS	NP_525111.1	Ferritin_like	74..393	CDD:469698	259/318 (81%)