Protein Alignment RRAD and Rgk2

DIOPT Version :10

• Sequence 1: NP_004156.1
• Gene: RRAD / 6236
• HGNCID: 10446
• Length: 308
• Species: Homo sapiens
• Sequence 2: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 90/257 - (35%)
• Similarity: 130/257 - (50%)
• Gaps: 47/257 - (18%)

Human    78 DSLSSGGSDSDE------SVYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVD-- 134
            |||.:...||:.      :.|:|::||..||||:||...|...|       ..||||.|:|:|
  Fly   507 DSLPATPDDSENLDPPPPARYRVVMLGDAGVGKTALVNQFMTSE-------YMHTYDASLVLDDE 564

Human   135 -GEEASLMVYDIWEQDG----------------GRWLPGHCMAMGDAYVIVYSVTDKGSFEKASE 182
             ||:...::.|..|.|.                ..:.|..|       |:|:||.|:.||..|.|
  Fly   565 FGEKTVSVLLDDEESDMVFIDHPSVEMSVENSLSTYEPHGC-------VVVFSVVDRSSFRVAEE 622

Human   183 LRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGV 247
            :...|.:...|.|..:||||||:||.|:|.::..||:|.|...|.||||||:.:.|||..|..|:
  Fly   623 IINYLWQENYTKDKAVILVGNKADLARARLITSQEGKALAASRDAKFIETSSGIQHNVDELLVGI 687

Human   248 VRQIRLR-RDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL 308
            ::|:||: :..|:|.|.:...:|...|| ..||..|.:|.      ::..:|||||.:|.||
  Fly   688 LKQMRLKEKREKKATASKMKTSRTHISL-HLAKELLQKIC------LSDISKSKSCENLHVL 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RRAD	NP_004156.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..88		4/9 (44%)
		RGK	92..308	CDD:206715	83/235 (35%)
		Calmodulin-binding	278..297		4/18 (22%)
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	83/235 (35%)