DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RRAD and rhb1

DIOPT Version :9

Sequence 1:	NP_001122322.1	Gene:	RRAD / 6236	HGNCID:	10446	Length:	308	Species:	Homo sapiens
Sequence 2:	NP_595194.1	Gene:	rhb1 / 2540853	PomBaseID:	SPBC428.16c	Length:	185	Species:	Schizosaccharomyces pombe

Alignment Length:	176	Identity:	60/176 - (34%)
Similarity:	94/176 - (53%)	Gaps:	18/176 - (10%)

- Green bases have known domain annotations that are detailed below.

Human    93 KVLLLGAPGVGKSALARIFGGVEDG------PEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDGG 151
            ::.:||:..||||:|...:  ||:.      |..|   :|:.::|...|:|.:..:.|...||..
pombe     8 RIAVLGSRSVGKSSLTVQY--VENHFVESYYPTIE---NTFSKNIKYKGQEFATEIIDTAGQDEY 67

Human   152 RWLPG-HCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSV 215
            ..|.. |.:.: ..||:|||:|.|.|||....:|.::.....|:.|||::|||||||...|.|:.
pombe    68 SILNSKHSIGI-HGYVLVYSITSKSSFEMVKIVRDKILNHTGTEWVPIVVVGNKSDLHMQRAVTA 131

Human   216 DEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEAN 261
            :||:|.|..:.|.:.|.||..:.||...||.::.:|     .|:||
pombe   132 EEGKALANEWKCAWTEASARHNENVARAFELIISEI-----EKQAN 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RRAD	NP_001122322.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..88
		RGK	92..308	CDD:206715	60/176 (34%)
		RAS	92..252	CDD:214541	56/165 (34%)
		Calmodulin-binding	278..297
rhb1	NP_595194.1	small_GTPase	5..170	CDD:197466	57/172 (33%)
rhb1	NP_595194.1	RheB	6..184	CDD:206709	60/176 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810