DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RPS5 and RpS5a

DIOPT Version :9

Sequence 1:	NP_001000.2	Gene:	RPS5 / 6193	HGNCID:	10426	Length:	204	Species:	Homo sapiens
Sequence 2:	NP_001285360.1	Gene:	RpS5a / 32700	FlyBaseID:	FBgn0002590	Length:	228	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	177/200 - (88%)
Similarity:	188/200 - (94%)	Gaps:	0/200 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     5 ETAAPAVAETPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIV 69
            ||...:..|.|:|||||:||.|||.:|||||||||:||||:|:||||||||||||||||||||||
  Fly    29 ETNVVSTTELPEIKLFGRWSCDDVTVNDISLQDYISVKEKFARYLPHSAGRYAAKRFRKAQCPIV 93

Human    70 ERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTV 134
            ||||.|:||.|||||||||..|||||:||||||||||||||:||:||||||||||||||||||||
  Fly    94 ERLTCSLMMKGRNNGKKLMACRIVKHSFEIIHLLTGENPLQILVSAIINSGPREDSTRIGRAGTV 158

Human   135 RRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERV 199
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   159 RRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERV 223

Human   200 AKSNR 204
            |||||
  Fly   224 AKSNR 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RPS5	NP_001000.2	uS7_Eukaryote	18..204	CDD:271246	170/185 (92%)
RpS5a	NP_001285360.1	uS7_Eukaryote	42..228	CDD:271246	170/185 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150887
Domainoid	1	1.000	267	1.000	Domainoid score	I1887
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H783
Inparanoid	1	1.050	355	1.000	Inparanoid score	I2241
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62189
OrthoDB	1	1.010	-	-		D1532160at2759
OrthoFinder	1	1.000	-	-		FOG0003144
OrthoInspector	1	1.000	-	-		otm41307
orthoMCL	1	0.900	-	-		OOG6_100920
Panther	1	1.100	-	-	O	PTHR11205
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2272
SonicParanoid	1	1.000	-	-		X2112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.900