DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BCS1L and smid

DIOPT Version :9

Sequence 1:	NP_001073335.1	Gene:	BCS1L / 617	HGNCID:	1020	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster

Alignment Length:	166	Identity:	48/166 - (28%)
Similarity:	86/166 - (51%)	Gaps:	19/166 - (11%)

- Green bases have known domain annotations that are detailed below.

Human   196 GLADRIVRDVQEF---IDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLT 257
            |..|..::::.|.   |.:|::|...|:...||.||:|||||||:....|::|:|:..:..:..|
  Fly   254 GGMDSTLKELCEMLIHIKSPEFYFQLGLLPSRGLLLHGPPGCGKTFLARAISGQLKMPLMEIPAT 318

Human   258 D-----SSLSDDRLNHLLSVAPQQS--LVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNA 315
            :     |..|::|:..:...|...|  ::.::::||...:|..|.::      :.|...|.|:::
  Fly   319 ELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKD------MERRIVSQLISS 377

Human   316 LDGVASTE---ARIVFMTTNHVDRLDPALIRPGRVD 348
            ||.:.:.|   :.:|...|...|.|||.|.|.||.|
  Fly   378 LDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFD 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BCS1L	NP_001073335.1	BCS1_N	24..191	CDD:214980
BCS1L	NP_001073335.1	RecA-like_BCS1	201..353	CDD:410918	46/161 (29%)
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	44/149 (30%)
		AAA	287..418	CDD:278434	39/133 (29%)
		P-loop_NTPase	679..>716	CDD:304359
		AAA	699..830	CDD:278434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910