DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RPL15 and RpL15

DIOPT Version :9

Sequence 1:	NP_001240308.1	Gene:	RPL15 / 6138	HGNCID:	10306	Length:	204	Species:	Homo sapiens
Sequence 2:	NP_001015155.1	Gene:	RpL15 / 3354918	FlyBaseID:	FBgn0028697	Length:	204	Species:	Drosophila melanogaster

Alignment Length:	204	Identity:	151/204 - (74%)
Similarity:	176/204 - (86%)	Gaps:	0/204 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIR 65
            ||||:|:|||:|||||||||:|||:|.||||||:.|||:||||||||||||||:||||:||||||
  Fly     1 MGAYRYMQELYRKKQSDVMRYLLRIRVWQYRQLTKLHRSPRPTRPDKARRLGYRAKQGFVIYRIR 65

Human    66 VRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFF 130
            |||||||||||||.|||||..|||||||..|.|||:||||.||..|.||||||||:.:|::||:|
  Fly    66 VRRGGRKRPVPKGCTYGKPKSHGVNQLKPYRGLQSIAEERVGRRLGGLRVLNSYWIAQDASYKYF 130

Human   131 EVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRR 195
            ||||||..|.||||:|...||.|.||||||:|||||||:.|||:|||:::..||||||||||:|:
  Fly   131 EVILIDTHHSAIRRDPKINWICKHVHKHRELRGLTSAGKSSRGIGKGYRYSQTIGGSRRAAWKRK 195

Human   196 NTLQLHRYR 204
            |...:||.|
  Fly   196 NREHMHRKR 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RPL15	NP_001240308.1	Ribosomal_L15e	2..191	CDD:395665	142/188 (76%)
RPL15	NP_001240308.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..186		12/20 (60%)
RpL15	NP_001015155.1	Ribosomal_L15e	2..191	CDD:395665	142/188 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151923
Domainoid	1	1.000	308	1.000	Domainoid score	I1348
eggNOG	1	0.900	-	-		E1_COG1632
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37713
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2480
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62174
OrthoDB	1	1.010	-	-		D1181691at2759
OrthoFinder	1	1.000	-	-		FOG0002642
OrthoInspector	1	1.000	-	-		oto91128
orthoMCL	1	0.900	-	-		OOG6_100733
Panther	1	1.100	-	-	LDO	PTHR11847
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1110
SonicParanoid	1	1.000	-	-		X1745
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800