Protein Alignment OPN1SW and ninaE

DIOPT Version :10

• Sequence 1: NP_001372054.1
• Gene: OPN1SW / 611
• HGNCID: 1012
• Length: 345
• Species: Homo sapiens
• Sequence 2: NP_524407.1
• Gene: ninaE / 42367
• FlyBaseID: FBgn0002940
• Length: 373
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 91/331 - (27%)
• Similarity: 153/331 - (46%)
• Gaps: 37/331 - (11%)

Human    27 PVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVA 91
            |:||..| .|:|..:.:|.:..|.:|:......|.||.|.|.:::|::...|.:.|.:. |:.
  Fly    47 PIWAKIL-TAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNT-PMM-- 107

Human    92 SCNGYF---VFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLA 153
            ..|.||   |.|..:|.:...||:..|..:.||:..::.:||.||.|.......:...||..:..
  Fly   108 GINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAY 172

Human   154 TWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYT 218
            .|.:.....:.|.|||||::|||...|||.|:  :...:...||..|..||.:.:||.|||:||.
  Fly   173 IWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDY--LERDWNPRSYLIFYSIFVYYIPLFLICYSYW 235

Human   219 QLLRALKAVAAQQQESA-------------TTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMV 270
            .::.|:.|.....:|.|             ..:.||.:::::.:|.:..:.:.:.|      |:|
  Fly   236 FIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTP------YLV 294

Human   271 NN-----RNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMK----MVCGKAMTDESDT 326
            .|     :..||........:.|:|||..||||:|...:.:::..:.:    .|.||....:|..
  Fly   295 INCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKSSD 359

Human   327 CSSQKT 332
            ..||.|
  Fly   360 AQSQAT 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OPN1SW	NP_001372054.1	7tmA_SWS1_opsin	32..311	CDD:320204	81/299 (27%)
		TM helix 1	33..59	CDD:320204	6/25 (24%)
		TM helix 2	66..93	CDD:320204	5/26 (19%)
		TM helix 3	104..134	CDD:320204	9/29 (31%)
		TM helix 4	145..167	CDD:320204	4/21 (19%)
		TM helix 5	194..224	CDD:320204	12/29 (41%)
		TM helix 6	239..269	CDD:320204	4/29 (14%)
		TM helix 7	279..304	CDD:320204	9/24 (38%)
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	81/299 (27%)
		TM helix 1	52..78	CDD:320207	6/26 (23%)
		TM helix 2	85..111	CDD:320207	5/28 (18%)
		TM helix 3	123..153	CDD:320207	9/29 (31%)
		TM helix 4	164..184	CDD:320207	3/19 (16%)
		TM helix 5	211..240	CDD:320207	12/28 (43%)
		TM helix 6	269..299	CDD:320207	7/35 (20%)
		TM helix 7	308..333	CDD:320207	9/24 (38%)