| Sequence 1: | NP_001185.3 | Gene: | HCN2 / 610 | HGNCID: | 4846 | Length: | 889 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_499033.1 | Gene: | tax-4 / 176297 | WormBaseID: | WBGene00006526 | Length: | 733 | Species: | Caenorhabditis elegans |
| Alignment Length: | 771 | Identity: | 167/771 - (21%) |
|---|---|---|---|
| Similarity: | 302/771 - (39%) | Gaps: | 199/771 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Human 49 PAPPQHPPRAEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAA------------------STA- 94
Human 95 ------KGSPNGECGRGEPQCS---PAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAG 150
Human 151 PAGEPRGSQASF------------------MQRQ-FGALLQP---GVNKFSLRMFGSQKAVE--- 190
Human 191 REQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFF 255
Human 256 LMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTW----FVVDFVSSIPVDYIF-----LIVEKG 311
Human 312 IDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRY--IHQWEEIFHMTYDLASAVMRICNLISMM 374
Human 375 LLLCHWDGCLQFLVPMLQDFPRNCWV-------SINGMVNHSWSELYSFALFKAMSHMLCIGYGR 432
Human 433 QAPESMTDI---WLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPA 494
Human 495 DFRQKIHDYYEHRYQGKM-FDEDSILGELNGPLREEI---VNFNCRKLVASMPLFANADPNFVTA 555
Human 556 MLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE--MKLSDGSYFGEICLL----- 613
Human 614 -TRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSIL------- 670
Human 671 ---LHKVQHDLNSGV-------------FNNQENAIIQEIVKYDREMVQQAELGQR 710 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HCN2 | NP_001185.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..159 | 28/137 (20%) | |
| Involved in subunit assembly. /evidence=ECO:0000250 | 158..209 | 13/75 (17%) | |||
| Ion_trans_N | 167..209 | CDD:285597 | 9/47 (19%) | ||
| Ion_trans | 229..474 | CDD:278921 | 55/265 (21%) | ||
| Crp | 538..>673 | CDD:223736 | 44/152 (29%) | ||
| CAP_ED | 544..652 | CDD:237999 | 39/115 (34%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 754..889 | ||||
| tax-4 | NP_499033.1 | Ion_trans | 197..421 | CDD:278921 | 60/280 (21%) |
| Crp | 487..680 | CDD:223736 | 49/199 (25%) | ||
| CAP_ED | 493..610 | CDD:237999 | 39/120 (33%) | ||
| CLZ | 609..675 | CDD:293134 | 9/65 (14%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C161452290 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.840 | |||||