Protein Alignment ROM1 and Tsp86D

DIOPT Version :9

• Sequence 1: NP_000318.2
• Gene: ROM1 / 6094
• HGNCID: 10254
• Length: 351
• Species: Homo sapiens
• Sequence 2: NP_001262468.1
• Gene: Tsp86D / 41310
• FlyBaseID: FBgn0037848
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 78/340 - (22%)
• Similarity: 126/340 - (37%)
• Gaps: 80/340 - (23%)

Human    21 LWLLSWLLALAGGVILLCSGHLLV-QLRHLGTFLAPSCQFPVLPQAALA---AGAVALGTGLVG- 80
            ::||::|..|.||::|....:..: :|.....:|.....:.|:...:|.   ||.:.......|
  Fly    35 IFLLNFLFWLFGGLLLAIGVYAFMDKLMDGNGWLRLDTIYDVIFNISLVMIIAGVIVFTVSFAGC 99

Human    81 VGASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVGLGLALAL-----PGSLDEALEEGLVTA 140
            :||.|.:       .|...|..:.:        ||...|.::||:     |..::..||......
  Fly   100 LGALREN-------TWLLKLYSMCL--------LLFFILEMSLAIICFVFPQYMNSFLEYQFTDK 149

Human   141 LAH-YKDTEVPGHCQAKRLVDELQLRYHCCG--RHGYKDWFGVQWVSSRYLDPGDRDVADRIQSN 202
            :.| |:|..     ..:..:|..|..::|||  ..||:|     |..:.|.:.....| :|.
  Fly   150 IIHSYRDDS-----DLQNFIDFAQQEFNCCGLSNAGYQD-----WSKNEYFNCSSPSV-ERC--- 200

Human   203 VEGLYLTDGVPFSCC-NPHSPRPCLQNRLSDSYAHPLFDPRQPNQNLWAQGCHEVLLEHLQ-DLA 265
                    |||:||| |.......|.| :...|...:......::.:|..||.|::...:: :|.
  Fly   201 --------GVPYSCCINATDISSGLVN-IMCGYGVQVRSVAAASKRIWTSGCIEIVRVWVERNLY 256

Human   266 GTLGSMLAVTFLLQALVLLGLRYLQTALEGLGGVIDAGGETQGYLFPSGLKDMLKTAWLQGGVAC 330
            ...|..|.:. |||..|:    ||...||                   |..|:.|:.|  . |.|
  Fly   257 VIAGVALGIA-LLQLFVI----YLAKTLE-------------------GQIDLQKSRW--SXVQC 295

Human   331 -RPAPEEAPPGEAPP 344
             .|.....||.|..|
  Fly   296 HHPYLYGYPPCEDDP 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ROM1	NP_000318.2	peripherin_like_LEL	126..265	CDD:239415	32/143 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..351		5/14 (36%)
Tsp86D	NP_001262468.1	Tetraspannin	51..283	CDD:278750	61/293 (21%)
		penumbra_like_LEL	132..255	CDD:239411	32/145 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910