DRSC/TRiP Functional Genomics Resources

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Protein Alignment ROBO1 and robo2

DIOPT Version :10

Sequence 1:XP_011532278.1 Gene:ROBO1 / 6091 HGNCID:10249 Length:1654 Species:Homo sapiens
Sequence 2:NP_001259868.1 Gene:robo2 / 44522 FlyBaseID:FBgn0002543 Length:1519 Species:Drosophila melanogaster


Alignment Length:23 Identity:7/23 - (30%)
Similarity:14/23 - (60%) Gaps:0/23 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    48 RVPEKLKVAPPNADLEQGFQEGV 70
            ::||..|::...|.:|...:||:
  Fly   446 KLPETSKMSIRQARIEFYKREGI 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ROBO1XP_011532278.1 IgC_1_Robo 68..166 CDD:409490 2/3 (67%)
Ig strand A 68..72 CDD:409490 2/3 (67%)
Ig strand A' 75..80 CDD:409490
Ig strand B 84..92 CDD:409490
Ig strand C 98..103 CDD:409490
Ig strand C' 106..108 CDD:409490
Ig strand D 119..122 CDD:409490
Ig strand E 125..131 CDD:409490
Ig strand F 143..151 CDD:409490
Ig strand G 154..166 CDD:409490
IgI_2_Robo 173..258 CDD:409389
Ig strand A 173..176 CDD:409389
Ig strand A' 178..182 CDD:409389
Ig strand B 186..193 CDD:409389
Ig strand C 201..206 CDD:409389
Ig strand C' 208..211 CDD:409389
Ig strand D 217..221 CDD:409389
Ig strand E 223..229 CDD:409389
Ig strand F 236..244 CDD:409389
Ig strand G 247..258 CDD:409389
IgI_3_Robo 265..347 CDD:409390
Ig strand A 265..268 CDD:409390
Ig strand A' 270..274 CDD:409390
Ig strand B 277..286 CDD:409390
Ig strand C 292..297 CDD:409390
Ig strand C' 300..303 CDD:409390
Ig strand D 306..311 CDD:409390
Ig strand E 312..319 CDD:409390
Ig strand F 326..334 CDD:409390
Ig strand G 337..347 CDD:409390
IgI_4_Robo 355..452 CDD:409391
Ig strand A 355..359 CDD:409391
Ig strand A' 361..365 CDD:409391
Ig strand B 371..379 CDD:409391
Ig strand C 382..389 CDD:409391
Ig strand C' 391..394 CDD:409391
Ig strand D 407..412 CDD:409391
Ig strand E 414..421 CDD:409391
Ig strand F 427..436 CDD:409391
FN3 428..882 CDD:442628
Ig strand G 438..449 CDD:409391
IgI_5_Robo 459..545 CDD:409544
Ig strand A 459..462 CDD:409544
Ig strand A' 466..469 CDD:409544
Ig strand B 475..482 CDD:409544
Ig strand C 488..493 CDD:409544
Ig strand C' 495..497 CDD:409544
Ig strand D 504..508 CDD:409544
Ig strand E 511..516 CDD:409544
Ig strand F 524..532 CDD:409544
Ig strand G 535..545 CDD:409544
FN3 564..650 CDD:238020
robo2NP_001259868.1 IgC_1_Robo 91..185 CDD:409490
Ig strand A 91..95 CDD:409490
Ig strand A' 98..103 CDD:409490
Ig strand B 107..115 CDD:409490
Ig strand C 121..126 CDD:409490
Ig strand C' 129..131 CDD:409490
Ig strand D 139..142 CDD:409490
Ig strand E 145..151 CDD:409490
Ig strand F 162..170 CDD:409490
Ig strand G 173..185 CDD:409490
IgI_2_Robo 192..279 CDD:409389
Ig strand A 192..195 CDD:409389
Ig strand A' 197..201 CDD:409389
Ig strand B 205..212 CDD:409389
Ig strand C 220..225 CDD:409389
Ig strand C' 227..230 CDD:409389
Ig strand D 237..241 CDD:409389
Ig strand E 244..250 CDD:409389
Ig strand F 257..265 CDD:409389
Ig strand G 268..279 CDD:409389
Ig 286..370 CDD:472250
Ig strand B 300..304 CDD:409353
Ig strand C 313..317 CDD:409353
Ig strand E 336..340 CDD:409353
Ig strand F 350..355 CDD:409353
Ig strand G 363..366 CDD:409353
Ig_3 373..457 CDD:464046 3/10 (30%)
Ig 480..566 CDD:472250
Ig strand B 496..500 CDD:409353
Ig strand C 509..513 CDD:409353
Ig strand E 533..537 CDD:409353
Ig strand F 548..553 CDD:409353
Ig strand G 561..564 CDD:409353
COG3979 586..>800 CDD:443178
FN3 588..681 CDD:238020
fn3 864..952 CDD:394996
Blue background indicates that the domain is not in the aligned region.

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