| Sequence 1: | XP_011532278.1 | Gene: | ROBO1 / 6091 | HGNCID: | 10249 | Length: | 1654 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_523731.2 | Gene: | tei / 36521 | FlyBaseID: | FBgn0000633 | Length: | 822 | Species: | Drosophila melanogaster |
| Alignment Length: | 562 | Identity: | 137/562 - (24%) |
|---|---|---|---|
| Similarity: | 203/562 - (36%) | Gaps: | 149/562 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Human 21 HLFLAQLIPDP-------EDVERGNDHGTPIPTSD-------------NDDNSLGYTGSRLRQED 65
Human 66 FPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR--SHRMLL-PSGSL 127
Human 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNA---SLEVA-------ILRDDFRQNPSDVMVA 182
Human 183 VGEPAVME--CQPPRGHPEPTISWKKDGSP-LDDKDERIT--------IRGGKL-----MITYTR 231
Human 232 KSDA-----------GKYVCVGTN-MVGERESEVAELTVLERPSF-VKRPSNLAVTVDDSAE--F 281
Human 282 KCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENM------VGKAE 340
Human 341 ASATLTVQVGSEPPHFVVKPRDQVVA----------------LGRTVTFQCEATGNPQPAIFWRR 389
Human 390 EGSQNLLFSYQPPQSSSR---FSVSQ-TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 450
Human 451 VIADRPPPVIRQGPVNQTVAVDGT-FVLSCVAT-----GSPV 486 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ROBO1 | XP_011532278.1 | IgC_1_Robo | 68..166 | CDD:409490 | 23/103 (22%) |
| Ig strand A | 68..72 | CDD:409490 | 1/3 (33%) | ||
| Ig strand A' | 75..80 | CDD:409490 | 1/4 (25%) | ||
| Ig strand B | 84..92 | CDD:409490 | 2/7 (29%) | ||
| Ig strand C | 98..103 | CDD:409490 | 2/4 (50%) | ||
| Ig strand C' | 106..108 | CDD:409490 | 0/1 (0%) | ||
| Ig strand D | 119..122 | CDD:409490 | 1/2 (50%) | ||
| Ig strand E | 125..131 | CDD:409490 | 2/5 (40%) | ||
| Ig strand F | 143..151 | CDD:409490 | 3/7 (43%) | ||
| Ig strand G | 154..166 | CDD:409490 | 3/14 (21%) | ||
| IgI_2_Robo | 173..258 | CDD:409389 | 26/112 (23%) | ||
| Ig strand A | 173..176 | CDD:409389 | 1/2 (50%) | ||
| Ig strand A' | 178..182 | CDD:409389 | 0/3 (0%) | ||
| Ig strand B | 186..193 | CDD:409389 | 1/8 (13%) | ||
| Ig strand C | 201..206 | CDD:409389 | 2/4 (50%) | ||
| Ig strand C' | 208..211 | CDD:409389 | 2/3 (67%) | ||
| Ig strand D | 217..221 | CDD:409389 | 0/11 (0%) | ||
| Ig strand E | 223..229 | CDD:409389 | 3/10 (30%) | ||
| Ig strand F | 236..244 | CDD:409389 | 2/7 (29%) | ||
| Ig strand G | 247..258 | CDD:409389 | 2/10 (20%) | ||
| IgI_3_Robo | 265..347 | CDD:409390 | 19/89 (21%) | ||
| Ig strand A | 265..268 | CDD:409390 | 0/2 (0%) | ||
| Ig strand A' | 270..274 | CDD:409390 | 0/3 (0%) | ||
| Ig strand B | 277..286 | CDD:409390 | 3/10 (30%) | ||
| Ig strand C | 292..297 | CDD:409390 | 3/4 (75%) | ||
| Ig strand C' | 300..303 | CDD:409390 | 1/2 (50%) | ||
| Ig strand D | 306..311 | CDD:409390 | 0/4 (0%) | ||
| Ig strand E | 312..319 | CDD:409390 | 2/6 (33%) | ||
| Ig strand F | 326..334 | CDD:409390 | 3/7 (43%) | ||
| Ig strand G | 337..347 | CDD:409390 | 1/9 (11%) | ||
| IgI_4_Robo | 355..452 | CDD:409391 | 30/116 (26%) | ||
| Ig strand A | 355..359 | CDD:409391 | 0/3 (0%) | ||
| Ig strand A' | 361..365 | CDD:409391 | 2/3 (67%) | ||
| Ig strand B | 371..379 | CDD:409391 | 4/7 (57%) | ||
| Ig strand C | 382..389 | CDD:409391 | 1/6 (17%) | ||
| Ig strand C' | 391..394 | CDD:409391 | 2/2 (100%) | ||
| Ig strand D | 407..412 | CDD:409391 | 1/7 (14%) | ||
| Ig strand E | 414..421 | CDD:409391 | 1/6 (17%) | ||
| Ig strand F | 427..436 | CDD:409391 | 3/8 (38%) | ||
| FN3 | 428..882 | CDD:442628 | 18/65 (28%) | ||
| Ig strand G | 438..449 | CDD:409391 | 4/10 (40%) | ||
| IgI_5_Robo | 459..545 | CDD:409544 | 10/34 (29%) | ||
| Ig strand A | 459..462 | CDD:409544 | 0/2 (0%) | ||
| Ig strand A' | 466..469 | CDD:409544 | 0/2 (0%) | ||
| Ig strand B | 475..482 | CDD:409544 | 1/6 (17%) | ||
| Ig strand C | 488..493 | CDD:409544 | |||
| Ig strand C' | 495..497 | CDD:409544 | |||
| Ig strand D | 504..508 | CDD:409544 | |||
| Ig strand E | 511..516 | CDD:409544 | |||
| Ig strand F | 524..532 | CDD:409544 | |||
| Ig strand G | 535..545 | CDD:409544 | |||
| FN3 | 564..650 | CDD:238020 | |||
| tei | NP_523731.2 | IG_like | 244..332 | CDD:214653 | 21/95 (22%) |
| Ig strand B | 254..258 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 267..271 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 296..300 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 310..315 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 326..329 | CDD:409353 | 0/2 (0%) | ||
| Ig | 359..452 | CDD:472250 | 20/92 (22%) | ||
| Ig_3 | 478..533 | CDD:464046 | 16/57 (28%) | ||
| IG_like | 578..660 | CDD:214653 | 29/113 (26%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||