DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BCL7A and BCL7-like

DIOPT Version :9

Sequence 1:	NP_066273.1	Gene:	BCL7A / 605	HGNCID:	1004	Length:	231	Species:	Homo sapiens
Sequence 2:	NP_572562.1	Gene:	BCL7-like / 31890	FlyBaseID:	FBgn0026149	Length:	154	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	62/163 - (38%)
Similarity:	84/163 - (51%)	Gaps:	31/163 - (19%)

- Green bases have known domain annotations that are detailed below.

Human     4 RSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKNKNKKKGKD 68
            |||||||||||||||||||.|::|||.|||||||:.||:::||||||:.       :.::||.|.
  Fly     3 RSVRAETRSRAKDDIKRVMQAVDKVRHWEKKWVTISDTTMKIYKWVPIA-------SASEKKAKL 60

Human    69 EKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPNSAVPS-DGTEAK- 131
            |            ||||...:...... |.:......|.:..::....|.|....|| .|..|:
  Fly    61 E------------SSPGSAAVRRPPPG-SGVTPVGGSKSDKENSQKGTPTPPQITPSYQGLTAED 112

Human   132 -------VDEAQADGKEHPGAEDASDEQNSQSS 157
                   |.::|  |.:...:...|::.|||.|
  Fly   113 SNTCFSVVSDSQ--GADFVSSMPFSEDSNSQGS 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BCL7A	NP_066273.1	BCL_N	4..50	CDD:398405	36/45 (80%)
BCL7-like	NP_572562.1	BCL_N	2..49	CDD:282557	36/45 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	88	1.000	Domainoid score	I7924
eggNOG	1	0.900	-	-		E1_KOG4095
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I5069
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1517597at2759
OrthoFinder	1	1.000	-	-		FOG0001798
OrthoInspector	1	1.000	-	-		otm41966
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12767
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2423
SonicParanoid	1	1.000	-	-		X1157
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.960