Protein Alignment FASTKD5 and CG13850

DIOPT Version :10

• Sequence 1: NP_068598.1
• Gene: FASTKD5 / 60493
• HGNCID: 25790
• Length: 764
• Species: Homo sapiens
• Sequence 2: NP_651038.3
• Gene: CG13850 / 42630
• FlyBaseID: FBgn0038961
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 739
• Identity: 138/739 - (18%)
• Similarity: 241/739 - (32%)
• Gaps: 283/739 - (38%)

Human    52 SAKKVKN--ICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFEN 114
            :|||.:.  :.:.|.|.|     :..|..|....:|||             :||..:
  Fly    54 AAKKPRGHMVAAAFESLR-----NDDPKDESKSQASSK-------------IDERII-------- 92

Human   115 MRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNL---QAQVIVDYLCKLSSLPAE 176
                            ||...:.||:::|          |.|..   .|..||..|.:.|:|...
  Fly    93 ----------------NAKTVNGLLTITE----------NNNGFSRKHALRIVSILAEWSTLNRV 131

Human   177 QHPVLLGSTSFALLCQL--------------------SVKKIQLFDTQDLINVLKAFVILGIPHS 221
            :.......|.|..:|::                    :.|:|..|.|.||..|      ||:...
  Fly   132 KISEFENDTRFLRICRMLGRTVPKNNNANNKDLGDNGTAKRISGFRTDDLNTV------LGVAGD 190

Human   222 HSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIY 286
            .                   :...|:|                          .:||.|:|.::.
  Fly   191 D-------------------EAAKLIA--------------------------SISLPQMVKVMS 210

Human   287 VIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHL 351
            .:.:.::.|..|::.|...|....:.::|::.|.:.  |..|:.|..:.|   :|...||::|..
  Fly   211 TLAQRKRRSTPLLRSLAFNISSASESLDLKQAGDVL--FAMSTLNFQDSV---LGAKVCADVQSA 270

Human   352 SSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAA 416
            ..:   |:.|            ...:|.|    |.|||:            ||:.:..::.::..
  Fly   271 LPK---NVEK------------SAVVGSI----ITSLGI------------LRYRDLDILESLTQ 304

Human   417 SLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHL----PTCLL 477
            .|......||.:|::....:...||:|....||....|:..|.|:  :|.:..|.|    ...:|
  Fly   305 WLLKNSEICRPQDLSAYFLTSALLNFKSAQLEEVSKKLVKSIVRE--DFTKQSEWLSFVWSLTML 367

Human   478 GLAFLEYFPVELIDFALSPGFVRLAQE-------RTKFDLLKELYTLDGTVGIECPDYRGNRLST 535
            ||  :|:..:..:   ||..|:...::       .:|..||    .|:....:...||:|..|.|
  Fly   368 GL--VEHGHLASV---LSADFLETLKKDKAGVTATSKMRLL----NLNSYAQLIATDYKGPLLPT 423

Human   536 HLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEV--QLDVNL 598
                                               ..|.|   .:.:.|.::..:.|  .||. |
  Fly   424 -----------------------------------DSPVY---QVPMAHPKAKQVLVNGMLDA-L 449

Human   599 KPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAV 663
            |.|      .||.|       |:..:: |..|..|:  .|..||    ::.....|::.||..|:
  Fly   450 KSL------LPASN-------HLQTAV-DTKMGFLI--DALCHF----DANKNPLPLDKENPNAI 494

Human   664 PLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGS-RDLLGLHNMKRRQLAR 727
                                            ::|:...:.:..|:|: |...|:.|:....|.:
  Fly   495 --------------------------------RVALMVIDFHDICHGTHRSGSGVTNLTFDLLEK 527

Human   728 LGYRVVELSYWEWL---PLLKRTR 748
            .||.|:.:.|.|:.   .||||.:
  Fly   528 SGYHVIPVPYNEFSTSDKLLKRVQ 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FASTKD5	NP_068598.1	RESC6-like	166..442	CDD:480594	50/295 (17%)
		FAST_1	430..503	CDD:461999	18/76 (24%)
		FAST_2	511..602	CDD:462448	15/92 (16%)
		RAP	699..758	CDD:214932	15/54 (28%)
CG13850	NP_651038.3	TBRG4-like_N	32..293	CDD:467932	67/377 (18%)
		FAST_1	318..387	CDD:461999	18/75 (24%)
		FAST_2	399..485	CDD:462448	28/148 (19%)
		RAP	498..556	CDD:214932	15/54 (28%)