Protein Alignment FASTKD5 and CG4619

DIOPT Version :10

• Sequence 1: NP_068598.1
• Gene: FASTKD5 / 60493
• HGNCID: 25790
• Length: 764
• Species: Homo sapiens
• Sequence 2: NP_609329.3
• Gene: CG4619 / 34321
• FlyBaseID: FBgn0032166
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 598
• Identity: 124/598 - (20%)
• Similarity: 216/598 - (36%)
• Gaps: 139/598 - (23%)

Human    88 ASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVR 152
            |....||.|                  :|.:..|.|...:.|  :.||..||:.....:.|.:.|
  Fly     9 AGVTNLGCP------------------IRTYASLTPRDVLRS--SDETGTLLTRFAKHIALERYR 53

Human   153 VNQNNLQAQV--------IVD---YLCKLSSLPAEQHPVLLGS--------------TSFALLCQ 192
            .:.:.|....        |.|   :...:....|.|.|.|:..              |:...|..
  Fly    54 DSDHVLPKTTVRYSDFFPITDDRYFQRTVEKTDAAQLPALIIQASSYRSNAAVPMYVTALNTLDN 118

Human   193 LSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRK 257
            .:.|::...||..::..|.:|:.| ||.....||.|:...          |.|:..|   :.|.|
  Fly   119 HAAKQLDKMDTATVLETLYSFLFL-IPSWIKRLDFYQAAM----------QRLVRED---FRGNK 169

Human   258 VPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTIC 322
             .||:.: ..|:.|..|                ..:.|::..|.||..:..::..:|..::..:.
  Fly   170 -ERFVQV-CFYMGLQKK----------------QAKSSEEFQQLLEEHLQTHLPELNEMDLAVVS 216

Human   323 LGFFKSSTNL-----SEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIA- 381
            ...:|:||.:     :.:..|.:..:....|...|...||:.||..|...|......:.:.:|.
  Fly   217 NAAYKTSTLVTGEAKTAYEARLVNAILNLEINTGSDALLVSFVKALRLQQVKDERVCQHLQDICL 281

Human   382 -PQRIPSLGVQGVMHL-TLYCSALRFLNE---GVMNAVAASLPPRVAHCRSKDVAKILWSFGTLN 441
             |.:|..:..:|:.|: ..:...|...||   .|:..:...|.|  ...||||:|..||:...||
  Fly   282 DPVKITHIEPRGLAHIFAFFAEQLWDQNECLTVVVKRLMTLLKP--GDLRSKDLATFLWASAQLN 344

Human   442 --YKPPNAEEFYSSLISEIHRKMP--EFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLA 502
              ..|....:...:.:    ||:.  |:..:|::|....|.|..|.::..:||:.|..   ::.|
  Fly   345 CALTPEEIRQLELTAL----RKLDHGEYEYFPDNLVDTCLSLCTLGHYSKDLINAAEE---LKAA 402

Human   503 QER----TKFDLLKELYTLDGTVGIECP------------DYRGNRLSTHLQQEGSELLWYLAEK 551
            |:|    .|.|  ..|..|...|.||.|            ::.|  ...:|.::..:|..|..|.
  Fly   403 QKRQRAQPKVD--SRLIVLRSAVAIEQPSIAKVKTERAFKEFDG--APAYLLKDRPDLTKYAQEL 463

Human   552 DMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNL-------KPLPFNREATP 609
            ..::..|.::.|.   .::|        :.||..|...:..|..|..       :.|.|:::.|.
  Fly   464 SGDADVEGVDVVC---PIVG--------INLPSLRVQTMGAQESVYFVELLTAEQTLKFSKKPTS 517

Human   610 AENVAKLRLEHVG 622
            ...:.|..||.:|
  Fly   518 LIRLKKRLLESLG 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FASTKD5	NP_068598.1	RESC6-like	166..442	CDD:480594	64/302 (21%)
		FAST_1	430..503	CDD:461999	17/76 (22%)
		FAST_2	511..602	CDD:462448	19/109 (17%)
		RAP	699..758	CDD:214932
CG4619	NP_609329.3	None