Protein Alignment FASTKD5 and CG31643

DIOPT Version :9

• Sequence 1: NP_068598.1
• Gene: FASTKD5 / 60493
• HGNCID: 25790
• Length: 764
• Species: Homo sapiens
• Sequence 2: NP_001285652.1
• Gene: CG31643 / 318867
• FlyBaseID: FBgn0051643
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 146/820 - (17%)
• Similarity: 253/820 - (30%)
• Gaps: 290/820 - (35%)

Human    46 HISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRA--TGVDEEDVEV 108
            ||:.|.||::|:.:.:.......|.........:...|...::..|...:|:|  ..:...::.|
  Fly   222 HINWCRSAEQVRLLSTCLFQLHFLIDEELFTRFKLRLTEMMQSGVLSSETPKALLKVIHMLNIPV 286

Human   109 FDSFENM---RVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCK- 169
            :......   .|.|.|||  .:|.   .|::.|.|:.  ...||       :.:...:::.|.|
  Fly   287 WSQTHTQLIREVMLVLRP--CIHQ---MESADLKSIC--RTFLH-------HQEPAALIEPLKKA 337

Human   170 LSSLPAEQHPVLLGSTSFALLC------------QLSVKKIQLFDTQ---------DLINVLKAF 213
            |..|..|:      .|:.||.|            .|...|..|:..:         .|.:||:|
  Fly   338 LEKLLQEE------GTADALFCAVPFATPLQRDQYLHQFKELLYSEEAWQQPNASGHLFSVLRA- 395

Human   214 VILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLH------ 272
                       |.|.:.:.|:..|...:.:|....:...:|     |||.....|:|.:
  Fly   396 -----------LKVSDIEFCNTYWSGVVKELESCPEKHLHL-----RFLRHCQRYMNFNNNLGGT 444

Human   273 WKDLSLSQLVHLIYVIGENRQVSQDLMQK---LESLILKYIDLINLEEVGTICLGFFKSSTNLSE 334
            ::.|.|.:.:..:.:......::..|..|   |.|.:|.|         |...|.:.|    ...
  Fly   445 YRHLELERKLSRMCMNAIEHDIAGRLPAKFARLASFVLAY---------GQTPLAWKK----FPN 496

Human   335 FVMRKIGDLACA---NIQ--HLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSL-GVQ-G 392
            |::.|:  ||.|   .||  .|.||.: .|....||.                |.:|:| |:| .
  Fly   497 FLLSKM--LAMAPQLGIQDCFLLSRGM-QIASELRFR----------------QHLPALAGMQLS 542

Human   393 VMHLTLYCSALRFLNEG---VMNAVAASLPPRV----------------------AHC---RSKD 429
            .|...|...|.|.|.:.   .:||...|:..|.                      .||   .|:.
  Fly   543 TMDSILIGCAERHLRDAEKDPLNASELSMIVRTLSHRKKLKNTVVYNQALAQYKNLHCNDLNSRV 607

Human   430 VAKILWSFGTLNYKPPNAEEFYSSLISEIHRK------------------MPEFNQYPEHLPTCL 476
            |..:.::|...|:..|...|...:.|||.|..                  ||...:...|....|
  Fly   608 VRDMAYNFNASNFFVPELLESMFAYISEQHDHVSGDTVEKVLTCSYNLGYMPASVEALNHASEVL 672

Human   477 ----------------LGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELY---------T 516
                            |.|.|.:..|.:||:......|::..::..:....|..|         .
  Fly   673 LRDFDQMSGLSVVQACLALCFYKSIPEQLINQVFCVKFIQRIEDEIQVCYSKATYPERVLNLVMQ 737

Human   517 LDGTVGIECPDYRGNRLSTHLQQEGSELLWY--------LAEKDMNSKPEFLETVFLLETMLGGP 573
            |:.||.::.|:              :.:.|:        :::|.:.......|...||..:|...
  Fly   738 LNRTVCLDFPE--------------ANVPWFQQNYIEAQISKKSLIPSESTTEVKQLLHQLLQND 788

Human   574 QYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKA 638
            ::.:.:...|:....|..:..|.:..|:|    |.|.|
  Fly   789 KHFRCNHTTPYGYQIDFVIHFDRDKNPIP----APPVE--------------------------- 822

Human   639 RGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTN 703
                                                             |.|.....|:|:....
  Fly   823 -------------------------------------------------ATMLDRITKVAILLLK 838

Human   704 RNQYCYGSRDLLGL---HNMKRRQLARLGYRVVELSYWEW 740
            .:.:|  ..||..|   .::|.|.|..:||:|::::..:|
  Fly   839 LDSFC--ENDLTALRGPESLKMRHLEMMGYKVMQINEHDW 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FASTKD5	NP_068598.1	FAST_1	431..499	CDD:310980	18/101 (18%)
		FAST_2	514..601	CDD:312018	14/103 (14%)
		RAP	699..758	CDD:214932	11/45 (24%)
CG31643	NP_001285652.1	FAST_1	647..713	CDD:284217	11/65 (17%)
		FAST_2	736..816	CDD:285557	13/93 (14%)
		RAP	834..894	CDD:214932	11/45 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21228
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010