Protein Alignment Matk and Src42A

DIOPT Version :10

• Sequence 1: XP_038935769.1
• Gene: Matk / 60450
• RGDID: 69058
• Length: 496
• Species: Rattus norvegicus
• Sequence 2: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 169/518 - (32%)
• Similarity: 241/518 - (46%)
• Gaps: 100/518 - (19%)

  Rat     2 PTQRWA----------PGTQ--CMTKCENSRPKPGELAFRKGDMVTILEACEDKSWYRAKHHS-- 52
            |.:||:          |.|:  .:|..|.||..|.              ||.....:...|.|
  Fly  1120 PLRRWSNQTPLKCTCHPATEELPLTAIEKSRSLPA--------------ACSASCSHTCAHLSVI 1170

  Rat    53 ---------SGQEGLLAAAALRQREALSTDPK---LSLMPWFHGKISGQEAIQQLQPPED--GLF 103
                     .|:..|..|...:.|. ||...:   |:...|:..||...||.::|..||:  |.|
  Fly  1171 DQSPATTKCFGKTSLTTAKKGKSRR-LSEFTRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAF 1234

  Rat   104 LVRESARHPGDYVLCVSFGRDVIHYRVLHRD-GHLTIDEAVCFCNLMDMVEHYTRDKGAICTKLV 167
            |:|:|.....||.|.|..|..|.|||:...| |...|.....|..|.::||||::|...:|..|.
  Fly  1235 LIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLC 1299

  Rat   168 KPKRKQGAKSAEEELAKA-----------GWLLDLQHLTLGAQIGEGEFGAVLQGEYLG-QKVAV 220
            ||..:..:.|...|:.|.           .|.:|...|....::|.|:||.|.:|.:.. ..||:
  Fly  1300 KPCVQTNSFSGVFEIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAI 1364

  Rat   221 KNIKC-DVTAQAFLDETAVMTKLQHRNLVRLLGV-ILHHGLYIVMEHVSKGNLVNFLRT---RGR 280
            |.:|. .:..:.||.|..:|.||:|..|::|..| .:...:||:.|.:..|:|:.:|:.   :||
  Fly  1365 KTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGR 1429

  Rat   281 ALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKA------ELRK 339
            :| ....|:..|..:|.||.||||:..:||||||||:||.:..:.|::|||||:.      |.|.
  Fly  1430 SL-KMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARV 1493

  Rat   340 GLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMVSSTPGRAACASRVTD 404
            |   :|.|:|||||||....:||.||||||||:||.|:.:|||.|||.|.::
  Fly  1494 G---ARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNA------------- 1542

  Rat   405 CPHPCYPLPPYLQSLKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKL 467
                            ||...||.||||..|.:|...::.:|..||..:|.|||.|..:..||
  Fly  1543 ----------------EVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKL 1589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Matk	XP_038935769.1	SH3	9..67	CDD:473055	13/70 (19%)
		SH2_csk_like	77..174	CDD:198190	36/99 (36%)
		Protein Kinases, catalytic domain	187..470	CDD:473864	109/293 (37%)
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233	34/90 (38%)
		PTKc_Frk_like	1328..1596	CDD:270653	109/295 (37%)