Protein Alignment CDH26 and Cdh26

DIOPT Version :10

• Sequence 1: NP_817089.1
• Gene: CDH26 / 60437
• HGNCID: 15902
• Length: 832
• Species: Homo sapiens
• Sequence 2: XP_008760731.1
• Gene: Cdh26 / 311693
• RGDID: 1311632
• Length: 787
• Species: Rattus norvegicus
• Alignment Length: 818
• Identity: 503/818 - (61%)
• Similarity: 604/818 - (73%)
• Gaps: 43/818 - (5%)

Human    20 WLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY 84
            |||.:..:...|.             :|||.|||||||:|||||:||||||||||:||||||||.
  Rat     8 WLLLLLSLPQGQS-------------HQPLHRSKRRWVLTTLELQEEDPGPFPKLVGELFNNMSK 59

Human    85 NMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSL 149
            |:||||||.||||||:|||||||:||.::|:|||||||||||||||.||||.|:|||||:||.||
  Rat    60 NVSLMYLIRGPGVDEFPEIGLFSIEDRQSGKIYVHRPVDREMTPSFMVYFDAVDRSTGKVVDESL 124

Human   150 IFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLK 214
            ||||||.||||||||||||||:|||:|:|:|||||||:|.||||:||||||||||||:||||||:
  Rat   125 IFNIRIRDVNDHAPQFPEKEFSITVKESQAAGQPIFQLLTVDLDQENTPNSQVLYFLVSQTPLLR 189

Human   215 ESGFRVDRLSGEIRLSGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQEN 279
            |||||:|.:|||:||||||.|||||:|||:|||.||||||||||.|:|:.|::.|||.|.||.::
  Rat   190 ESGFRIDLISGEVRLSGCLHYETAPRFTLIIRASDCGEPSLSSTATIHISVEDSNNHMPTFTDDH 254

Human   280 YKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLD 344
            |.:||.||:..:.||.|.|.|.|||||.|||.:|||..|||||||||:||||||:|:|::|||||
  Rat   255 YTIQISEGQVERDVLYLPVHDGDSPFTPAWRTQFNIWDGNEEGHFDITTDPETNQGLLSIIKPLD 319

Human   345 YETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGA 409
            |||:.|.||:|||||:|:|..|:.|:|||.|||.||.||||||.|.||||||||:||||::|:||
  Rat   320 YETQVAHSLLIVVENQEQLFNCQEGQLQPLRKAMASTTVSVQVLDTNDPPAFHPRSFIVSEEDGA 384

Human   410 RPGTLLGTFNAMDP---DSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIH 471
            .|...||.|||.||   |||||||||.||.|||:||:.||.|.|...|||||||||.|||.|::|
  Rat   385 WPAIQLGYFNATDPDRADSQIRYELVRDPENWVTVDEKSGEVTTKRQIDRESPHVNGSFYTIVVH 449

Human   472 AVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTF 536
            |:|:|.||.|.||||||||.|:|||.|.|:|.||::|:||||.::.|.:||||.||:|::.||||
  Rat   450 AIDNGLPPLTGTGTLMLFLYDVNDNAPILQPHSRHLEICESAGNKALLLEAEDADLDPYAGPFTF 514

Human   537 ELDNTWGNAEDTW--KLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCAS 599
            :||:..|:..:.|  ::.:..|.|.||:..||||.|:|||||||||:|||:||||||||||.|.|
  Rat   515 DLDSDQGDVREIWMLRIKQEEGHSAELIMRRSLPPGDYLVPLFIGDRQGLAQKQTVHVRICSCPS 579

Human   600 GLTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYN 664
            |..|.|.:|.  ||...||.|||||.:||:.:||.|||||.|..|||....:.:|.|||||::.|
  Rat   580 GSDCEEHSDP--GLLWWALSPVCAAVMALSASLLGLLRCYCVFGPKRLRGFIPSDSGHQTLIVSN 642

Human   665 AESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFE 729
            .|:|..|||.....|.|..||....|.|....|||                       |.|..||
  Rat   643 EETKALSAQMQPAGEDQMLALSFNRAVASAKPGVK-----------------------GCGMFFE 684

Human   730 PRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPHVYSEEGECGGAP 794
            ||..||:.|||.|.:..:.|:.|...|||:.|..:|||...:|||.|.|.|||||.|||||.||.
  Rat   685 PRGAKNLTSTPIYLERMVPRRPLQLTEGRVVEMWSQKLQGVDVLEGDTGDLPHVYREEGECEGAE 749

Human   795 SLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 832
            :||||..|||:|..:||||.|||:||.|.:...|.|||
  Rat   750 TLSSLTFLEQDLSSELLDSSGSKSTPPEAMCFTSRVPS 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDH26	NP_817089.1	Cadherin_repeat	<85..161	CDD:206637	61/75 (81%)
		Cadherin_repeat	169..271	CDD:206637	77/101 (76%)
		Cadherin_repeat	280..392	CDD:206637	73/111 (66%)
		Cadherin_repeat	407..496	CDD:206637	60/91 (66%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	813..832		9/18 (50%)
Cdh26	XP_008760731.1	Cadherin_repeat	<60..136	CDD:206637	61/75 (81%)
		Cadherin_repeat	144..246	CDD:206637	77/101 (76%)
		Cadherin_repeat	254..367	CDD:206637	73/112 (65%)
		Cadherin_repeat	393..474	CDD:206637	55/80 (69%)