| Sequence 1: | NP_066956.1 | Gene: | RNASEL / 6041 | HGNCID: | 10050 | Length: | 741 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001072537.1 | Gene: | eif2ak2 / 779992 | XenbaseID: | XB-GENE-1001011 | Length: | 552 | Species: | Xenopus tropicalis |
| Alignment Length: | 503 | Identity: | 107/503 - (21%) |
|---|---|---|---|
| Similarity: | 188/503 - (37%) | Gaps: | 112/503 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Human 154 RRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDV 218
Human 219 EAITHLLLDHGADVNVRGER----GKTPLILAVEKKHLGLVQ--------RLLEQEHIEI---ND 268
Human 269 TDSDGKTALLLAVELKLK-----KIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGAKED 328
Human 329 F------HP--------------------PAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDE 367
Human 368 KYKIADTSEGGIYLGFYEK--QEVAVKTFCEGSPRAQR-------EVSCLQSSRENSHLVTFYGS 423
Human 424 ESHRGHLFVCVTLCEQ-TLEACLDVHRGEDVENEEDEFARNVL-SSIFKAVQELHLSCGYTHQDL 486
Human 487 QPQNILIDSKKAAHLADFDKSIKWAG--DPQEVKR-----------------------DLEDLGR 526
Human 527 LVL---YVVKKGSISFEDLKAQSNEEV----VQLSPDEET--KDLIHR 565 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RNASEL | NP_066956.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
| ANK repeat | 24..56 | CDD:293786 | |||
| ANK 1 | 24..53 | ||||
| Ank_2 | 29..122 | CDD:289560 | |||
| ANK 2 | 58..87 | ||||
| ANK | 59..188 | CDD:238125 | 9/33 (27%) | ||
| ANK repeat | 59..89 | CDD:293786 | |||
| ANK repeat | 91..122 | CDD:293786 | |||
| ANK 3 | 91..120 | ||||
| Ank_2 | 96..199 | CDD:289560 | 10/44 (23%) | ||
| ANK repeat | 124..154 | CDD:293786 | 107/503 (21%) | ||
| ANK 4 | 124..153 | ||||
| ANK repeat | 167..199 | CDD:293786 | 6/31 (19%) | ||
| ANK 5 | 167..197 | 6/29 (21%) | |||
| Ank_2 | 172..270 | CDD:289560 | 21/112 (19%) | ||
| ANK | 196..321 | CDD:238125 | 27/144 (19%) | ||
| ANK repeat | 201..236 | CDD:293786 | 7/34 (21%) | ||
| ANK 6 | 201..234 | 6/32 (19%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 4/16 (25%) | |||
| ANK 7 | 238..268 | 7/44 (16%) | |||
| Ank_2 | 243..326 | CDD:289560 | 20/98 (20%) | ||
| 2-5A binding (P-loop) 2 | 253..275 | 5/32 (16%) | |||
| ANK repeat | 272..326 | CDD:293786 | 13/58 (22%) | ||
| ANK 8 | 272..301 | 9/33 (27%) | |||
| ANK 9 | 303..329 | 5/25 (20%) | |||
| PKc_like | 375..587 | CDD:304357 | 56/236 (24%) | ||
| Pkinase | 387..586 | CDD:278497 | 54/222 (24%) | ||
| RNase_RNase-L | 590..708 | CDD:199218 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..741 | ||||
| eif2ak2 | NP_001072537.1 | DSRM_RNAse_III_family | 5..71 | CDD:380682 | 7/29 (24%) |
| DSRM_EIF2AK2-like | 118..183 | CDD:380704 | 12/64 (19%) | ||
| PKc_like | 269..541 | CDD:389743 | 63/268 (24%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||