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Protein Alignment RNASEL and ankef1a

DIOPT Version :9

Sequence 1:	NP_066956.1	Gene:	RNASEL / 6041	HGNCID:	10050	Length:	741	Species:	Homo sapiens
Sequence 2:	NP_001020714.1	Gene:	ankef1a / 566413	ZFINID:	ZDB-GENE-041001-196	Length:	779	Species:	Danio rerio

Alignment Length:	634	Identity:	133/634 - (20%)
Similarity:	214/634 - (33%)	Gaps:	208/634 - (32%)

- Green bases have known domain annotations that are detailed below.

Human    20 RAAVEDNHLLIKAVQNEDVDLVQQLLEGGAN--VNFQEEEGGWTPLHNAVQMSREDIVELLLRHG 82
            |..|...:.|::.:|:.|...:::|:..|.:  :|..|...|...||.|...::.|::|.|:..|
Zfish     9 RLQVLQIYRLLQCIQDGDKTYIEKLISMGVDDLINLTEPRDGNGVLHLAAVTNKPDMLEFLVDQG 73

Human    83 ADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECD-------FY---------------- 124
            |.|.::.::|.||.:|||..|...::.|...|.||:...|       ||
Zfish    74 ARPDVQDRSGRTPLMLAAELGYDGIVSLLAKKNADMKLVDIEGKGVLFYCLHPTKRHMRCLQVVL 138

Human   125 ------------------------------------------------GFTAFMEAAVYGKVKAL 141
                                                            |.||.||||..|.::.:
Zfish   139 NGNADVNNVSEAGIPVFLLACEQAQDCEGMCLSILERGADPNATNQETGRTALMEAARAGALELV 203

Human   142 KFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNAL 206
            :.:.|:|.|||..     |::|..     |...|||||..|::|: |....|||......|...|
Zfish   204 RAILKKGGNVNAL-----DKKRFH-----AAHFAAEKGFFEIIKV-LSAYRADVGGVTTEGDTPL 257

Human   207 IHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQE--HIEINDT 269
             |...|...:|   ....|...|.:..::.:.|..|..:|.:..|...|:.|.:.|  |.:.:..
Zfish   258 -HFAASGGYTD---CCRFLAQRGCNPKLKNQEGLLPRQIAKDCGHKATVKELKKAERLHGKSSKG 318

Human   270 DSDGKTALLL-----------------------AVELKLK-KIAELLCKRGASTDCGD------- 303
            .::|..||:|                       .||...| ....:|.:..|..|  |
Zfish   319 GTNGPWALMLHDWSHENENELRSAFESATDGFIGVEFVPKGTFVSVLKELHAPLD--DVQIHILL 381

Human   304 LVMTARR----NYDHSL--------VKVLLSHGAK------------------------------ 326
            |.:..||    |.:..|        ..|:.|:|.|
Zfish   382 LALDKRREGFININDFLRGLKYLPKTYVMASYGPKKKKAAKAGKTKKSKFNLPLPICTVPQDLIH 446

Human   327 --EDFHPP---AEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKI-------ADTSE-GG 378
              :|..||   .|.|: .::......:| ||..||:.....::|||..||       ..|.: ..
Zfish   447 RRDDGGPPHFMIESWQ-HATDTQRYDRD-HRPERPIEDDTAWYIDEPEKIYINLNYCVKTGDIES 509

Human   379 IYLGFYEKQEVAVKTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQ---- 439
            :.|...:|..|.||.....:|..   .:|...:.|.:..:...|::         |..|:|
Zfish   510 LRLALSQKVPVDVKDRFYKTPLM---AACASGNYEMAKFLLDNGAD---------VNACDQFKWT 562

Human   440 -TLEACLDVHRGE--------DVENEEDEFARNVLSSIFKAVQELHLSC 479
             ...||   |.|:        :.....|..|.|..:.:.:|::....||
Zfish   563 PLHHAC---HAGQLDIIQLLLEAGASVDRPALNGATPLMRAIESCRPSC 608

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.