DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNASEL and pskh1

DIOPT Version :9

Sequence 1:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens
Sequence 2:NP_001017030.1 Gene:pskh1 / 549784 XenbaseID:XB-GENE-947381 Length:416 Species:Xenopus tropicalis


Alignment Length:328 Identity:78/328 - (23%)
Similarity:134/328 - (40%) Gaps:85/328 - (25%)


- Green bases have known domain annotations that are detailed below.


Human   386 KQEVAVK---TFC-EGSPRAQREVSCLQSSRENS--HLVTFYGSESH---------RGHLFVCVT 435
            ||..|:|   |.| ||....:.|::.|:..|..:  .|:..:.|:..         .|.||..: 
 Frog   113 KQPYAIKMIETKCREGREVCESELNVLRRVRHTNIIQLIEVFESQERVYMVMELATGGELFDRI- 176

Human   436 LCEQTLEACLDVHRGEDVENEEDEFARNVLSSIFKAVQELHLSCGYTHQDLQPQNIL-----IDS 495
                       :.:|...|.:    |.:||..:.:.|:.|| :.|.||:||:|:|:|     |||
 Frog   177 -----------ITKGSFTERD----ATHVLQMVLEGVKYLH-ALGITHRDLKPENLLYYHPGIDS 225

Human   496 KKAAHLADFD-KSIKWAGD---------------PQEVKR-------DLEDLGRLVLYVVKKGSI 537
            |  ..:.||. .|.:..||               |:.:.|       |:..|| ::.|::..|::
 Frog   226 K--IMITDFGLASAQKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALG-VISYILLSGTM 287

Human   538 SFED----------LKAQ---SNEEVVQLSPDEETKDLIHRLF--HPGEHVRDCLSDLLGHPFFW 587
            .|||          |:.:   |.|....:|  ...||.|.||.  .||:  |...:..|.||:..
 Frog   288 PFEDDNRTRLYRQILRGKYSYSGEPWPSVS--NLAKDFIDRLLMVEPGQ--RMTATHALKHPWIV 348

Human   588 TW--ESRYRTLRNVGNESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINECVMKKMNKFYEK 650
            :.  .|..:.|....:::.:|...|..:..:..|...|..|....| :.::.|..::::|..|::
 Frog   349 SMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSIHSSRSTKSSK-SRRVRERELRELNLRYQQ 412

Human   651 RGN 653
            ..|
 Frog   413 HYN 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
ANK repeat 24..56 CDD:293786
ANK 1 24..53
Ank_2 29..122 CDD:289560
ANK 2 58..87
ANK 59..188 CDD:238125
ANK repeat 59..89 CDD:293786
ANK repeat 91..122 CDD:293786
ANK 3 91..120
Ank_2 96..199 CDD:289560
ANK repeat 124..154 CDD:293786
ANK 4 124..153
ANK repeat 167..199 CDD:293786
ANK 5 167..197
Ank_2 172..270 CDD:289560
ANK 196..321 CDD:238125
ANK repeat 201..236 CDD:293786
ANK 6 201..234
2-5A binding (P-loop) 1 229..242
ANK 7 238..268
Ank_2 243..326 CDD:289560
2-5A binding (P-loop) 2 253..275
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357 66/258 (26%)
Pkinase 387..586 CDD:278497 65/256 (25%)
RNase_RNase-L 590..708 CDD:199218 12/64 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
pskh1NP_001017030.1 STKc_PSKH1 88..347 CDD:270989 66/257 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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