DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNASEL and sdr39u1

DIOPT Version :9

Sequence 1:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens
Sequence 2:NP_001016261.1 Gene:sdr39u1 / 549015 XenbaseID:XB-GENE-1015181 Length:300 Species:Xenopus tropicalis


Alignment Length:266 Identity:53/266 - (19%)
Similarity:82/266 - (30%) Gaps:105/266 - (39%)


- Green bases have known domain annotations that are detailed below.


Human   397 GSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLF------VCVTLCEQTLEACLDVHRGEDVEN 455
            ||....:.:|.|.:||  .|.||.......:|.:.      :.:..|:..:...     ||:|.|
 Frog     8 GSGFIGQSLSKLLNSR--GHKVTIVSRRPGKGRITWEDVSKIGLPPCDAAVNLA-----GENVLN 65

Human   456 E----EDEFARNVLSS-------IFKAVQE---------LHLSCGY-----THQ----------- 484
            .    .::|.:.|:||       :.:|:.:         |....||     |||           
 Frog    66 PLKRWTEKFKQEVISSRIETTRTLTQAISKSPNPPQSWILVTGVGYYPPSQTHQYSEESPGGDAD 130

Human   485 -------------DLQPQNILIDSKKAAHLADFDK------------SIKW-----------AGD 513
                         :|.|.|    ||.:..|.....            |:.|           :|:
 Frog   131 FLSRLVRDWEQVAELSPSN----SKSSTQLVRVRSGVVLGRDGGALPSMLWPFRLCLGGPIGSGN 191

Human   514 PQEVKRDLEDLGRLVLYVVKKGSISFEDLKAQSNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLS 578
            .......:|||.||:...:::|..|...|.|.|...|         ||       ...:....||
 Frog   192 QPFPWIHIEDLCRLLCQCIEQGGCSEAILNAVSPSSV---------KD-------TNSNFTQALS 240

Human   579 DLLGHP 584
            ..||.|
 Frog   241 RALGRP 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
ANK repeat 24..56 CDD:293786
ANK 1 24..53
Ank_2 29..122 CDD:289560
ANK 2 58..87
ANK 59..188 CDD:238125
ANK repeat 59..89 CDD:293786
ANK repeat 91..122 CDD:293786
ANK 3 91..120
Ank_2 96..199 CDD:289560
ANK repeat 124..154 CDD:293786
ANK 4 124..153
ANK repeat 167..199 CDD:293786
ANK 5 167..197
Ank_2 172..270 CDD:289560
ANK 196..321 CDD:238125
ANK repeat 201..236 CDD:293786
ANK 6 201..234
2-5A binding (P-loop) 1 229..242
ANK 7 238..268
Ank_2 243..326 CDD:289560
2-5A binding (P-loop) 2 253..275
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357 53/266 (20%)
Pkinase 387..586 CDD:278497 53/266 (20%)
RNase_RNase-L 590..708 CDD:199218
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
sdr39u1NP_001016261.1 SDR_a8 2..299 CDD:187553 53/266 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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