| Sequence 1: | NP_066956.1 | Gene: | RNASEL / 6041 | HGNCID: | 10050 | Length: | 741 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_593384.1 | Gene: | ire1 / 2542776 | PomBaseID: | SPAC167.01 | Length: | 1072 | Species: | Schizosaccharomyces pombe |
| Alignment Length: | 572 | Identity: | 126/572 - (22%) |
|---|---|---|---|
| Similarity: | 227/572 - (39%) | Gaps: | 152/572 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Human 226 LDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEH---IEINDTDSDGKTALLLAVELKLKK 287
Human 288 IAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGAKEDFHPPAEDWKPQSSHWGAALKDLHR 352
Human 353 IYRPMIGKLKFFIDEKYKIADTSEGGI-YLGFYEKQEVAVK-TFCEGSPRAQREVSCLQSSRENS 415
Human 416 HLVTFYGSESHRGHLFVCVTLCEQTLEACL-------DVHRGEDVENEEDEFARNVLSSIFKAVQ 473
Human 474 ELHLSCGYTHQDLQPQNILIDSKKAAHLA-----------------DFDKS------IKWAG--- 512
Human 513 --DPQ-------------EVK------------RDLEDLGRLVLYVVKKGSISF------EDLKA 544
Human 545 QSNEEVVQLSPDEE----TKDLIHRL--FHPGEHVRDCLSDLLGHPFFWTWESRYRTLRNVGNES 603
Human 604 DIKTRKSESEILRLLQPGPSEHSKSF--DKWTTKINECVMKKMNKFYEKRGNFYQNTVGDLLKFI 666
Human 667 RNLGEHIDEEKHKKMKLKIGD-P---SLYFQKTFPDLVIYVYTKLQNTEYRK 714 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RNASEL | NP_066956.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
| ANK repeat | 24..56 | CDD:293786 | |||
| ANK 1 | 24..53 | ||||
| Ank_2 | 29..122 | CDD:289560 | |||
| ANK 2 | 58..87 | ||||
| ANK | 59..188 | CDD:238125 | |||
| ANK repeat | 59..89 | CDD:293786 | |||
| ANK repeat | 91..122 | CDD:293786 | |||
| ANK 3 | 91..120 | ||||
| Ank_2 | 96..199 | CDD:289560 | |||
| ANK repeat | 124..154 | CDD:293786 | |||
| ANK 4 | 124..153 | ||||
| ANK repeat | 167..199 | CDD:293786 | |||
| ANK 5 | 167..197 | ||||
| Ank_2 | 172..270 | CDD:289560 | 7/46 (15%) | ||
| ANK | 196..321 | CDD:238125 | 17/97 (18%) | ||
| ANK repeat | 201..236 | CDD:293786 | 1/9 (11%) | ||
| ANK 6 | 201..234 | 1/7 (14%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 4/12 (33%) | |||
| ANK 7 | 238..268 | 4/32 (13%) | |||
| Ank_2 | 243..326 | CDD:289560 | 13/85 (15%) | ||
| 2-5A binding (P-loop) 2 | 253..275 | 4/24 (17%) | |||
| ANK repeat | 272..326 | CDD:293786 | 9/53 (17%) | ||
| ANK 8 | 272..301 | 5/28 (18%) | |||
| ANK 9 | 303..329 | 3/25 (12%) | |||
| PKc_like | 375..587 | CDD:304357 | 70/285 (25%) | ||
| Pkinase | 387..586 | CDD:278497 | 63/271 (23%) | ||
| RNase_RNase-L | 590..708 | CDD:199218 | 28/123 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..741 | 126/572 (22%) | |||
| ire1 | NP_593384.1 | Luminal_IRE1_like | 82..440 | CDD:276097 | |
| STKc_IRE1 | 652..939 | CDD:270884 | 74/311 (24%) | ||
| S_TKc | 658..938 | CDD:214567 | 72/303 (24%) | ||
| RNase_Ire1 | 942..1070 | CDD:199217 | 29/131 (22%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1027 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||