| Sequence 1: | NP_066956.1 | Gene: | RNASEL / 6041 | HGNCID: | 10050 | Length: | 741 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036012.1 | Gene: | Rnasel / 24014 | MGIID: | 1098272 | Length: | 735 | Species: | Mus musculus |
| Alignment Length: | 736 | Identity: | 475/736 - (64%) |
|---|---|---|---|
| Similarity: | 572/736 - (77%) | Gaps: | 8/736 - (1%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MESRDHNNPQEGPTSSSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHN 65
Human 66 AVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFM 130
Human 131 EAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADV 195
Human 196 NACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLE 260
Human 261 QEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGA 325
Human 326 KEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIYLGFYEKQEVA 390
Human 391 VKTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVHRGEDVEN 455
Human 456 EEDEFARNVLSSIFKAVQELHLSCGYTHQDLQPQNILIDSKKAAHLADFDKSIKWAGDPQEVKRD 520
Human 521 LEDLGRLVLYVVKKGSISFEDLKAQSNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLSDLLGHPF 585
Human 586 FWTWESRYRTLRNVGNESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINECVMKKMNKFYEK 650
Human 651 R-GNFYQNTVGDLLKFIRNLGEHIDEEKHKKMKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRK 714
Human 715 HFPQTHSPNK---PQCDGAGG 732 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RNASEL | NP_066956.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | 8/19 (42%) | |
| ANK repeat | 24..56 | CDD:293786 | 19/31 (61%) | ||
| ANK 1 | 24..53 | 18/28 (64%) | |||
| Ank_2 | 29..122 | CDD:289560 | 65/92 (71%) | ||
| ANK 2 | 58..87 | 22/28 (79%) | |||
| ANK | 59..188 | CDD:238125 | 92/128 (72%) | ||
| ANK repeat | 59..89 | CDD:293786 | 22/29 (76%) | ||
| ANK repeat | 91..122 | CDD:293786 | 22/30 (73%) | ||
| ANK 3 | 91..120 | 20/28 (71%) | |||
| Ank_2 | 96..199 | CDD:289560 | 68/102 (67%) | ||
| ANK repeat | 124..154 | CDD:293786 | 19/29 (66%) | ||
| ANK 4 | 124..153 | 18/28 (64%) | |||
| ANK repeat | 167..199 | CDD:293786 | 23/31 (74%) | ||
| ANK 5 | 167..197 | 22/29 (76%) | |||
| Ank_2 | 172..270 | CDD:289560 | 66/97 (68%) | ||
| ANK | 196..321 | CDD:238125 | 77/124 (62%) | ||
| ANK repeat | 201..236 | CDD:293786 | 22/34 (65%) | ||
| ANK 6 | 201..234 | 20/32 (63%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 12/12 (100%) | |||
| ANK 7 | 238..268 | 21/29 (72%) | |||
| Ank_2 | 243..326 | CDD:289560 | 46/82 (56%) | ||
| 2-5A binding (P-loop) 2 | 253..275 | 11/21 (52%) | |||
| ANK repeat | 272..326 | CDD:293786 | 29/53 (55%) | ||
| ANK 8 | 272..301 | 15/28 (54%) | |||
| ANK 9 | 303..329 | 14/25 (56%) | |||
| PKc_like | 375..587 | CDD:304357 | 137/211 (65%) | ||
| Pkinase | 387..586 | CDD:278497 | 129/198 (65%) | ||
| RNase_RNase-L | 590..708 | CDD:199218 | 81/118 (69%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..741 | 9/21 (43%) | |||
| Rnasel | NP_036012.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | 8/19 (42%) | |
| ANK repeat | 24..55 | CDD:293786 | 19/30 (63%) | ||
| ANK 1 | 24..53 | 18/28 (64%) | |||
| Binding to TMEV Leader protein. /evidence=ECO:0000269|PubMed:29652922 | 26..51 | 16/24 (67%) | |||
| Ank_2 | <29..88 | CDD:403870 | 40/58 (69%) | ||
| ANK 2 | 58..87 | 22/28 (79%) | |||
| ANK repeat | 59..89 | CDD:293786 | 22/29 (76%) | ||
| Ank_2 | 61..>298 | CDD:423045 | 159/236 (67%) | ||
| ANK repeat | 91..122 | CDD:293786 | 22/30 (73%) | ||
| ANK 3 | 91..120 | 20/28 (71%) | |||
| ANK repeat | 124..154 | CDD:293786 | 19/29 (66%) | ||
| ANK 4 | 124..153 | 18/28 (64%) | |||
| ANK repeat | 167..199 | CDD:293786 | 23/31 (74%) | ||
| ANK 5 | 167..197 | 22/29 (76%) | |||
| ANK 6 | 201..234 | 20/32 (63%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 12/12 (100%) | |||
| ANK repeat | 238..270 | CDD:293786 | 21/31 (68%) | ||
| ANK 7 | 238..268 | 21/29 (72%) | |||
| 2-5A binding (P-loop) 2 | 253..275 | 11/21 (52%) | |||
| ANK 8 | 272..301 | 15/29 (52%) | |||
| ANK repeat | 272..297 | CDD:293786 | 13/24 (54%) | ||
| ANK 9 | 303..328 | 13/24 (54%) | |||
| PKc_like | 361..585 | CDD:419665 | 145/224 (65%) | ||
| RNase_RNase-L | 588..707 | CDD:199218 | 81/118 (69%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 714..735 | 9/21 (43%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83956032 | |
| Domainoid | 1 | 1.000 | 182 | 1.000 | Domainoid score | I28083 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1027 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H8040 | |
| Inparanoid | 1 | 1.050 | 918 | 1.000 | Inparanoid score | I6605 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG36966 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0013115 | |
| OrthoInspector | 1 | 1.000 | - | - | oto123526 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_127805 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24141 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R13349 |
| SonicParanoid | 1 | 1.000 | - | - | X13352 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 18.290 | |||||