| Sequence 1: | NP_066956.1 | Gene: | RNASEL / 6041 | HGNCID: | 10050 | Length: | 741 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_493429.2 | Gene: | trp-4 / 190574 | WormBaseID: | WBGene00006616 | Length: | 1924 | Species: | Caenorhabditis elegans |
| Alignment Length: | 732 | Identity: | 154/732 - (21%) |
|---|---|---|---|
| Similarity: | 251/732 - (34%) | Gaps: | 205/732 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Human 25 DNHLLIK-AVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMS---REDIVELLLRHGADP 85
Human 86 VLRKKNGATPFILAAIAGSVKLLKLFLSKGAD---------------VNECDFY----------- 124
Human 125 -----------------GFTAFMEAAVYGK---------VKALKFLYKRGANVNLRRKTKED--- 160
Human 161 ---------------------------QERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNAC 198
Human 199 DNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEH 263
Human 264 IEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGD------LVMTARRNYDHSLVKVLLS 322
Human 323 HGAKEDFHPPAEDWKPQSSHWG-------------AALKDLHRIYRPMIGKLKFFIDEKYKIADT 374
Human 375 SEGGIYLGFYEKQEVAVKTFCEGSPRAQRE----------------VSCLQS---------SREN 414
Human 415 S----HLVTFYGSESHRGHLFVCVTLCEQTLEACLDVHRGEDVENE-------------EDEFAR 462
Human 463 NVL--------SSIFKAVQELHLSCGYTHQDLQPQNILIDSKKAAHLADFDKSIKWAG-DPQEVK 518
Human 519 RDLEDLGRLVLYVVKKGSISFEDLKA---------QSNEEVVQL------SPDEETKD----LIH 564
Human 565 RLFHPGEHVRDCLSDLL 581 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RNASEL | NP_066956.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
| ANK repeat | 24..56 | CDD:293786 | 10/31 (32%) | ||
| ANK 1 | 24..53 | 10/28 (36%) | |||
| Ank_2 | 29..122 | CDD:289560 | 28/111 (25%) | ||
| ANK 2 | 58..87 | 10/31 (32%) | |||
| ANK | 59..188 | CDD:238125 | 40/213 (19%) | ||
| ANK repeat | 59..89 | CDD:293786 | 10/32 (31%) | ||
| ANK repeat | 91..122 | CDD:293786 | 9/45 (20%) | ||
| ANK 3 | 91..120 | 9/43 (21%) | |||
| Ank_2 | 96..199 | CDD:289560 | 31/184 (17%) | ||
| ANK repeat | 124..154 | CDD:293786 | 10/66 (15%) | ||
| ANK 4 | 124..153 | 10/65 (15%) | |||
| ANK repeat | 167..199 | CDD:293786 | 10/31 (32%) | ||
| ANK 5 | 167..197 | 10/29 (34%) | |||
| Ank_2 | 172..270 | CDD:289560 | 33/97 (34%) | ||
| ANK | 196..321 | CDD:238125 | 37/130 (28%) | ||
| ANK repeat | 201..236 | CDD:293786 | 15/34 (44%) | ||
| ANK 6 | 201..234 | 14/32 (44%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 4/12 (33%) | |||
| ANK 7 | 238..268 | 8/29 (28%) | |||
| Ank_2 | 243..326 | CDD:289560 | 20/88 (23%) | ||
| 2-5A binding (P-loop) 2 | 253..275 | 3/21 (14%) | |||
| ANK repeat | 272..326 | CDD:293786 | 14/59 (24%) | ||
| ANK 8 | 272..301 | 8/28 (29%) | |||
| ANK 9 | 303..329 | 6/31 (19%) | |||
| PKc_like | 375..587 | CDD:304357 | 51/277 (18%) | ||
| Pkinase | 387..586 | CDD:278497 | 49/265 (18%) | ||
| RNase_RNase-L | 590..708 | CDD:199218 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..741 | ||||
| trp-4 | NP_493429.2 | ANK repeat | 804..842 | CDD:293786 | 10/37 (27%) |
| ANK repeat | 849..884 | CDD:293786 | 1/34 (3%) | ||
| ANK repeat | 886..917 | CDD:293786 | 10/31 (32%) | ||
| ANK repeat | 919..950 | CDD:293786 | 15/34 (44%) | ||
| ANK repeat | 952..982 | CDD:293786 | 8/29 (28%) | ||
| ANK repeat | 986..1017 | CDD:293786 | 8/30 (27%) | ||
| PHA03095 | 1006..>1336 | CDD:222980 | 61/351 (17%) | ||
| ANK repeat | 1092..1123 | CDD:293786 | 7/38 (18%) | ||
| ANK repeat | 1204..1236 | CDD:293786 | 3/31 (10%) | ||
| trp | 1209..1879 | CDD:273311 | 33/161 (20%) | ||
| ANK repeat | 1238..1270 | CDD:293786 | 8/32 (25%) | ||
| ANK repeat | 1272..1303 | CDD:293786 | 4/30 (13%) | ||
| ANK repeat | 1305..1336 | CDD:293786 | 4/30 (13%) | ||
| ANK repeat | 1338..1366 | CDD:293786 | 7/25 (28%) | ||
| ANKYR | 280..515 | CDD:223738 | |||
| ANK repeat | 352..383 | CDD:293786 | |||
| ANK repeat | 385..418 | CDD:293786 | |||
| ANK repeat | 424..454 | CDD:293786 | |||
| PHA03095 | 430..>756 | CDD:222980 | 30/97 (31%) | ||
| ANK repeat | 456..489 | CDD:293786 | |||
| ANK repeat | 491..523 | CDD:293786 | |||
| ANK repeat | 526..556 | CDD:293786 | |||
| ANK repeat | 558..590 | CDD:293786 | |||
| ANK repeat | 592..623 | CDD:293786 | |||
| ANK repeat | 625..656 | CDD:293786 | |||
| ANK repeat | 658..688 | CDD:293786 | 10/29 (34%) | ||
| ANK repeat | 692..726 | CDD:293786 | 10/33 (30%) | ||
| PHA02876 | <712..>1040 | CDD:165207 | 74/333 (22%) | ||
| ANK repeat | 728..753 | CDD:293786 | 7/24 (29%) | ||
| ANK repeat | 761..802 | CDD:293786 | 2/40 (5%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4177 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||