DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNASEL and dhhc-13

DIOPT Version :9

Sequence 1:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens
Sequence 2:NP_500889.2 Gene:dhhc-13 / 186797 WormBaseID:WBGene00019257 Length:593 Species:Caenorhabditis elegans


Alignment Length:209 Identity:65/209 - (31%)
Similarity:92/209 - (44%) Gaps:44/209 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    17 SGRRAAVEDNH----LLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVEL 77
            :|..:|.|.:|    ||..|..|..:|::|.||...|::|........||||.|...|:...|..
 Worm    56 NGHVSANEFDHEGCGLLHWAAINNKLDIIQLLLSHRADINLIGGNMKSTPLHWACYNSQFGAVMA 120

Human    78 LLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNEC-DFYGFTAFMEAA-------- 133
            |:::||||.::..||.||..|||..|:..::...|.|..::.:. |..|.:|.|.||        
 Worm   121 LVKNGADPTIKNINGETPLHLAACTGNFIIIAYLLVKFDNIKDTRDNLGRSALMMAADKSFGLFP 185

Human   134 --VYGKVKA-LKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAE----KGHVEVLKILLDEM 191
              ::.||.| |.|               .|.|:    |.|||...|.    ||.||::.     .
 Worm   186 IRIFTKVDAYLDF---------------TDDEK----GNTALHILAARQNLKGVVELIC-----S 226

Human   192 GADVNACDNMGRNA 205
            |||....||.|.:|
 Worm   227 GADDTKTDNNGVSA 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21 1/3 (33%)
ANK repeat 24..56 CDD:293786 12/35 (34%)
ANK 1 24..53 11/32 (34%)
Ank_2 29..122 CDD:289560 31/93 (33%)
ANK 2 58..87 12/28 (43%)
ANK 59..188 CDD:238125 44/144 (31%)
ANK repeat 59..89 CDD:293786 12/29 (41%)
ANK repeat 91..122 CDD:293786 10/31 (32%)
ANK 3 91..120 10/28 (36%)
Ank_2 96..199 CDD:289560 31/118 (26%)
ANK repeat 124..154 CDD:293786 10/40 (25%)
ANK 4 124..153 10/39 (26%)
ANK repeat 167..199 CDD:293786 12/35 (34%)
ANK 5 167..197 12/33 (36%)
Ank_2 172..270 CDD:289560 13/38 (34%)
ANK 196..321 CDD:238125 4/10 (40%)
ANK repeat 201..236 CDD:293786 2/5 (40%)
ANK 6 201..234 2/5 (40%)
2-5A binding (P-loop) 1 229..242
ANK 7 238..268
Ank_2 243..326 CDD:289560
2-5A binding (P-loop) 2 253..275
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357
Pkinase 387..586 CDD:278497
RNase_RNase-L 590..708 CDD:199218
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
dhhc-13NP_500889.2 ANK 42..155 CDD:238125 34/98 (35%)
Ank_2 42..132 CDD:289560 26/75 (35%)
ANK repeat 67..98 CDD:293786 10/30 (33%)
ANK repeat 101..132 CDD:293786 12/30 (40%)
Ank_5 121..176 CDD:290568 19/54 (35%)
ANK 130..>240 CDD:238125 38/133 (29%)
Ank_5 198..243 CDD:290568 19/67 (28%)
ANK repeat 206..234 CDD:293786 11/32 (34%)
zf-DHHC 405..530 CDD:279823
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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