| Sequence 1: | NP_066956.1 | Gene: | RNASEL / 6041 | HGNCID: | 10050 | Length: | 741 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001300226.1 | Gene: | nphp-2 / 178671 | WormBaseID: | WBGene00021304 | Length: | 834 | Species: | Caenorhabditis elegans |
| Alignment Length: | 753 | Identity: | 162/753 - (21%) |
|---|---|---|---|
| Similarity: | 284/753 - (37%) | Gaps: | 164/753 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Human 15 SSSGRRAAVED---NHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVE 76
Human 77 --------LLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAA 133
Human 134 VYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVE-VLKILLDEMGADVNA 197
Human 198 CDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQE 262
Human 263 HIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTD--CG-------DLVMTARRNY---DHS 315
Human 316 LVKVLLSHGAKEDFHPP-AEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGI 379
Human 380 YLGFYEKQEVA----------VKTFCEGSPR------------------AQREVSCLQSSRENSH 416
Human 417 LVTFYGSESHRGHLFV---------CVTLCEQTLEACLDVHRGEDVENEEDEFARNVLSSIFKAV 472
Human 473 QELHLSCGYTHQDLQPQNILIDSKKAAHLADFDKSIKWAGD-PQEVKRDLE---DLGRLVLYVVK 533
Human 534 KGSISFEDLKAQSNEEVVQLSPD-------------------------------EETKDLIHRLF 567
Human 568 HPGEH-------VRDCLS--------DLLGHPF--FWTWESRYRTLRNVGNES----DIKTRKSE 611
Human 612 SEILRLLQPGPSEHSKSFDKWTTKINECVMKKMNKFYE 649 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RNASEL | NP_066956.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | 1/5 (20%) | |
| ANK repeat | 24..56 | CDD:293786 | 7/34 (21%) | ||
| ANK 1 | 24..53 | 6/31 (19%) | |||
| Ank_2 | 29..122 | CDD:289560 | 27/100 (27%) | ||
| ANK 2 | 58..87 | 15/36 (42%) | |||
| ANK | 59..188 | CDD:238125 | 41/137 (30%) | ||
| ANK repeat | 59..89 | CDD:293786 | 15/37 (41%) | ||
| ANK repeat | 91..122 | CDD:293786 | 6/30 (20%) | ||
| ANK 3 | 91..120 | 6/28 (21%) | |||
| Ank_2 | 96..199 | CDD:289560 | 27/103 (26%) | ||
| ANK repeat | 124..154 | CDD:293786 | 8/29 (28%) | ||
| ANK 4 | 124..153 | 7/28 (25%) | |||
| ANK repeat | 167..199 | CDD:293786 | 13/32 (41%) | ||
| ANK 5 | 167..197 | 11/30 (37%) | |||
| Ank_2 | 172..270 | CDD:289560 | 25/98 (26%) | ||
| ANK | 196..321 | CDD:238125 | 31/136 (23%) | ||
| ANK repeat | 201..236 | CDD:293786 | 6/34 (18%) | ||
| ANK 6 | 201..234 | 6/32 (19%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 3/12 (25%) | |||
| ANK 7 | 238..268 | 8/29 (28%) | |||
| Ank_2 | 243..326 | CDD:289560 | 19/94 (20%) | ||
| 2-5A binding (P-loop) 2 | 253..275 | 4/21 (19%) | |||
| ANK repeat | 272..326 | CDD:293786 | 14/65 (22%) | ||
| ANK 8 | 272..301 | 9/30 (30%) | |||
| ANK 9 | 303..329 | 6/28 (21%) | |||
| PKc_like | 375..587 | CDD:304357 | 50/300 (17%) | ||
| Pkinase | 387..586 | CDD:278497 | 47/287 (16%) | ||
| RNase_RNase-L | 590..708 | CDD:199218 | 16/64 (25%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..741 | ||||
| nphp-2 | NP_001300226.1 | ANK repeat | 39..67 | CDD:293786 | |
| PHA02874 | 46..>361 | CDD:165205 | 73/286 (26%) | ||
| ANK repeat | 69..100 | CDD:293786 | 2/9 (22%) | ||
| ANK repeat | 103..133 | CDD:293786 | 6/29 (21%) | ||
| ANK repeat | 135..173 | CDD:293786 | 15/39 (38%) | ||
| ANK repeat | 175..206 | CDD:293786 | 6/30 (20%) | ||
| Ank_2 | 180..274 | CDD:372319 | 28/107 (26%) | ||
| ANK repeat | 208..241 | CDD:293786 | 9/40 (23%) | ||
| ANK repeat | 243..274 | CDD:293786 | 14/36 (39%) | ||
| ANK repeat | 276..307 | CDD:293786 | 6/30 (20%) | ||
| ANK repeat | 343..377 | CDD:293786 | 10/33 (30%) | ||
| PTZ00108 | <414..650 | CDD:240271 | 47/257 (18%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||