| Sequence 1: | NP_066956.1 | Gene: | RNASEL / 6041 | HGNCID: | 10050 | Length: | 741 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_009291264.1 | Gene: | ank3a / 103909035 | ZFINID: | ZDB-GENE-060621-1 | Length: | 4499 | Species: | Danio rerio |
| Alignment Length: | 739 | Identity: | 166/739 - (22%) |
|---|---|---|---|
| Similarity: | 282/739 - (38%) | Gaps: | 207/739 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Human 5 DHNNPQEGP-----TSSSG---------------------RRAAVE-----DNHLLIKAVQNEDV 38
Human 39 DLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRK-KNGATPFILAAIA 102
Human 103 GSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKG 167
Human 168 GATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADV 232
Human 233 NVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRG- 296
Human 297 ---ASTDCG--DLVMTARRNYDHSLVKVLLSHGA------KEDFHPPAEDWKPQSSHWGAALKDL 350
Human 351 HRIYRPMIGKLK---FFIDEKYKIADTSEGGI----YLGFYEKQEVAVKTFCEG-SPRAQRE--- 404
Human 405 ----VSCLQSSRENSHLVTFYGSE----SHRG----HLFV---CVTLCEQTLEACLDVHRGEDVE 454
Human 455 NEEDEFARNVLSSIFKAVQE--------------------------LHLSCGYTHQDLQPQNILI 493
Human 494 DSK------------------KAAHLADFDKSIKWAGDPQEVKRDLEDLGRLVLYVVKK-GSISF 539
Human 540 ED-LKAQSNE--------------------EVVQLSPDEETKDLIHRLFHPGEHVRDCLSDLLGH 583
Human 584 PFFWTWES----RYRTLRNVGNES 603 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RNASEL | NP_066956.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | 8/41 (20%) | |
| ANK repeat | 24..56 | CDD:293786 | 7/36 (19%) | ||
| ANK 1 | 24..53 | 7/33 (21%) | |||
| Ank_2 | 29..122 | CDD:289560 | 30/93 (32%) | ||
| ANK 2 | 58..87 | 13/28 (46%) | |||
| ANK | 59..188 | CDD:238125 | 41/129 (32%) | ||
| ANK repeat | 59..89 | CDD:293786 | 14/29 (48%) | ||
| ANK repeat | 91..122 | CDD:293786 | 8/30 (27%) | ||
| ANK 3 | 91..120 | 8/28 (29%) | |||
| Ank_2 | 96..199 | CDD:289560 | 27/102 (26%) | ||
| ANK repeat | 124..154 | CDD:293786 | 10/29 (34%) | ||
| ANK 4 | 124..153 | 9/28 (32%) | |||
| ANK repeat | 167..199 | CDD:293786 | 12/31 (39%) | ||
| ANK 5 | 167..197 | 11/29 (38%) | |||
| Ank_2 | 172..270 | CDD:289560 | 28/97 (29%) | ||
| ANK | 196..321 | CDD:238125 | 34/130 (26%) | ||
| ANK repeat | 201..236 | CDD:293786 | 9/34 (26%) | ||
| ANK 6 | 201..234 | 8/32 (25%) | |||
| 2-5A binding (P-loop) 1 | 229..242 | 5/12 (42%) | |||
| ANK 7 | 238..268 | 9/29 (31%) | |||
| Ank_2 | 243..326 | CDD:289560 | 24/94 (26%) | ||
| 2-5A binding (P-loop) 2 | 253..275 | 5/21 (24%) | |||
| ANK repeat | 272..326 | CDD:293786 | 18/65 (28%) | ||
| ANK 8 | 272..301 | 11/32 (34%) | |||
| ANK 9 | 303..329 | 7/31 (23%) | |||
| PKc_like | 375..587 | CDD:304357 | 51/300 (17%) | ||
| Pkinase | 387..586 | CDD:278497 | 49/283 (17%) | ||
| RNase_RNase-L | 590..708 | CDD:199218 | 6/18 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..741 | ||||
| ank3a | XP_009291264.1 | Ank_4 | 48..95 | CDD:290365 | |
| ANK | 69..194 | CDD:238125 | |||
| ANK repeat | 74..105 | CDD:293786 | |||
| Ank_2 | 79..169 | CDD:289560 | |||
| ANK repeat | 107..138 | CDD:293786 | |||
| ANK repeat | 140..169 | CDD:293786 | |||
| Ank_2 | 145..271 | CDD:289560 | 10/44 (23%) | ||
| ANK repeat | 206..241 | CDD:293786 | 4/14 (29%) | ||
| ANK | 238..363 | CDD:238125 | 35/126 (28%) | ||
| ANK repeat | 243..274 | CDD:293786 | 6/30 (20%) | ||
| Ank_2 | 248..339 | CDD:289560 | 25/92 (27%) | ||
| ANK repeat | 276..307 | CDD:293786 | 7/30 (23%) | ||
| ANK repeat | 309..340 | CDD:293786 | 14/32 (44%) | ||
| ANK | 338..461 | CDD:238125 | 35/133 (26%) | ||
| ANK repeat | 342..373 | CDD:293786 | 8/30 (27%) | ||
| Ank_2 | 347..438 | CDD:289560 | 26/101 (26%) | ||
| ANK repeat | 375..406 | CDD:293786 | 10/40 (25%) | ||
| ANK | 403..528 | CDD:238125 | 38/140 (27%) | ||
| ANK repeat | 408..439 | CDD:293786 | 12/31 (39%) | ||
| Ank_2 | 413..504 | CDD:289560 | 28/96 (29%) | ||
| ANK repeat | 441..472 | CDD:293786 | 9/34 (26%) | ||
| ANK | 469..594 | CDD:238125 | 35/146 (24%) | ||
| ANK repeat | 474..505 | CDD:293786 | 9/31 (29%) | ||
| Ank_2 | 479..569 | CDD:289560 | 24/91 (26%) | ||
| ANK repeat | 507..536 | CDD:293786 | 9/28 (32%) | ||
| ANK repeat | 540..569 | CDD:293786 | 7/29 (24%) | ||
| Ank_2 | 545..634 | CDD:289560 | 21/109 (19%) | ||
| ANK | 569..693 | CDD:238125 | 25/143 (17%) | ||
| ANK repeat | 573..602 | CDD:293786 | 7/48 (15%) | ||
| ANK repeat | 606..634 | CDD:293786 | 7/27 (26%) | ||
| ANK repeat | 639..670 | CDD:293786 | 4/30 (13%) | ||
| Ank_4 | 640..693 | CDD:290365 | 9/52 (17%) | ||
| ANK | 667..792 | CDD:238125 | 19/136 (14%) | ||
| ANK repeat | 675..703 | CDD:293786 | 6/27 (22%) | ||
| Ank_2 | 677..768 | CDD:289560 | 17/102 (17%) | ||
| ANK repeat | 705..736 | CDD:293786 | 4/30 (13%) | ||
| ANK repeat | 738..769 | CDD:293786 | 6/32 (19%) | ||
| Ank_5 | 758..812 | CDD:290568 | 6/57 (11%) | ||
| ANK repeat | 771..799 | CDD:293786 | 1/27 (4%) | ||
| ZU5 | 995..1099 | CDD:128514 | |||
| Death_ank3 | 3886..3969 | CDD:176781 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4177 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||