DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNASEL and bard1

DIOPT Version :9

Sequence 1:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens
Sequence 2:XP_017952998.2 Gene:bard1 / 100498289 XenbaseID:XB-GENE-492035 Length:781 Species:Xenopus tropicalis


Alignment Length:201 Identity:55/201 - (27%)
Similarity:87/201 - (43%) Gaps:18/201 - (8%)


- Green bases have known domain annotations that are detailed below.


Human    23 VEDNH----LLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGA 83
            |:.||    :|..|....|:..|:.||:.|||.|. ::..||||||.|..:....||||||:|.|
 Frog   423 VKRNHKGETMLHLASIKGDIQGVEDLLKSGANPNV-KDNAGWTPLHEACNLGHTVIVELLLQHHA 486

Human    84 DPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 148
            ..........||...|...|.:.:::|.||.||.....:.:|... ::.|...|:|::....:..
 Frog   487 LVNTTGYQNDTPLHDAVKNGHIAIVQLLLSHGASQEAVNIFGLQP-VDYAETEKMKSVLLETQTT 550

Human   149 ANVNLRRKTKEDQERLRKGG-----ATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIH 208
            .|..|.|...|.....||..     |:.|:........::.|.|..|:.|:.:       ..:.|
 Frog   551 RNRLLLRPCLEPSSHQRKEETVVLIASGLLATQRADLTKLAKTLKAEVCAEYD-------GKVTH 608

Human   209 ALLSSD 214
            .::|.:
 Frog   609 VIVSDE 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
ANK repeat 24..56 CDD:293786 12/35 (34%)
ANK 1 24..53 11/32 (34%)
Ank_2 29..122 CDD:289560 34/92 (37%)
ANK 2 58..87 15/28 (54%)
ANK 59..188 CDD:238125 37/133 (28%)
ANK repeat 59..89 CDD:293786 15/29 (52%)
ANK repeat 91..122 CDD:293786 9/30 (30%)
ANK 3 91..120 9/28 (32%)
Ank_2 96..199 CDD:289560 23/107 (21%)
ANK repeat 124..154 CDD:293786 5/29 (17%)
ANK 4 124..153 5/28 (18%)
ANK repeat 167..199 CDD:293786 6/36 (17%)
ANK 5 167..197 6/34 (18%)
Ank_2 172..270 CDD:289560 7/43 (16%)
ANK 196..321 CDD:238125 2/19 (11%)
ANK repeat 201..236 CDD:293786 2/14 (14%)
ANK 6 201..234 2/14 (14%)
2-5A binding (P-loop) 1 229..242
ANK 7 238..268
Ank_2 243..326 CDD:289560
2-5A binding (P-loop) 2 253..275
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357
Pkinase 387..586 CDD:278497
RNase_RNase-L 590..708 CDD:199218
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
bard1XP_017952998.2 RING-HC_BARD1 41..84 CDD:319410
PHA02876 <324..>532 CDD:165207 38/110 (35%)
ANK repeat 429..459 CDD:293786 10/30 (33%)
Ank_2 433..525 CDD:403870 34/92 (37%)
ANK repeat 461..492 CDD:293786 15/30 (50%)
ANK repeat 494..525 CDD:293786 9/30 (30%)
BRCT_Bard1_rpt1 572..648 CDD:349366 8/50 (16%)
BRCT_Bard1_rpt2 673..773 CDD:349352
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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