DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNASEL and stk39

DIOPT Version :9

Sequence 1:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens
Sequence 2:XP_017953089.2 Gene:stk39 / 100488948 XenbaseID:XB-GENE-1012528 Length:609 Species:Xenopus tropicalis


Alignment Length:366 Identity:80/366 - (21%)
Similarity:129/366 - (35%) Gaps:130/366 - (35%)


- Green bases have known domain annotations that are detailed below.


Human   384 YEKQEV------AVKTFCEGSPRAQREV-------SC----------LQSSRENSH--LVTFYGS 423
            ||.|||      ||.......||.:|..       .|          :|:..:.||  :||:|.|
 Frog   128 YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNIVTYYTS 192

Human   424 ESHRGHLFVCVTLCEQTLEACLD-----VHRGEDVENE-EDEFARNVLSSIFKAVQELHLSCGYT 482
            ...:..|::.:.|...  .:.||     |.|||..... |:.....:|..:.:.:..||.: |..
 Frog   193 FVVKEELWLVMKLLSG--GSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRN-GQI 254

Human   483 HQDLQPQNILIDSKKAAHLADFDKS--IKWAGDPQEVKRDLEDLGRLVLYVVKKGSISFEDLKAQ 545
            |:||:..|||:....:..:|||..|  :...||....|             |:|   :|......
 Frog   255 HRDLKAGNILLGEDGSVQIADFGVSSFLATGGDVTRNK-------------VRK---TFVGTPCW 303

Human   546 SNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLSDLLGHPF---FW----------TWESRYR--- 594
            ...||:                   |.||       |:.|   .|          |..:.|.   
 Frog   304 MAPEVM-------------------EQVR-------GYDFKADMWSFGITAIELATGAAPYHKYP 342

Human   595 -------TLRNVGNESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINECVMKKMNKFYEKRG 652
                   ||:|  :...::|...:.|::|       ::.|||.|   .|:.|:.|..:|      
 Frog   343 PMKVLMLTLQN--DPPTLETGVEDKEMMR-------KYGKSFRK---LISLCLQKDPSK------ 389

Human   653 NFYQNTVGDLLKFIRNLGEHIDEEKHKKM---KLKIGDPSL 690
               :.|..:|||.     :...:.|:::.   ||.|..|::
 Frog   390 ---RPTAAELLKC-----KFFQKSKNREYLIEKLLIKTPNI 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
ANK repeat 24..56 CDD:293786
ANK 1 24..53
Ank_2 29..122 CDD:289560
ANK 2 58..87
ANK 59..188 CDD:238125
ANK repeat 59..89 CDD:293786
ANK repeat 91..122 CDD:293786
ANK 3 91..120
Ank_2 96..199 CDD:289560
ANK repeat 124..154 CDD:293786
ANK 4 124..153
ANK repeat 167..199 CDD:293786
ANK 5 167..197
Ank_2 172..270 CDD:289560
ANK 196..321 CDD:238125
ANK repeat 201..236 CDD:293786
ANK 6 201..234
2-5A binding (P-loop) 1 229..242
ANK 7 238..268
Ank_2 243..326 CDD:289560
2-5A binding (P-loop) 2 253..275
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357 54/238 (23%)
Pkinase 387..586 CDD:278497 52/234 (22%)
RNase_RNase-L 590..708 CDD:199218 24/114 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
stk39XP_017953089.2 STKc_OSR1_SPAK 126..402 CDD:270787 75/344 (22%)
OSR1_C 516..573 CDD:403428
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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