DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNASEL and snrk

DIOPT Version :9

Sequence 1:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens
Sequence 2:NP_001123824.1 Gene:snrk / 100170575 XenbaseID:XB-GENE-1005804 Length:764 Species:Xenopus tropicalis


Alignment Length:355 Identity:74/355 - (20%)
Similarity:128/355 - (36%) Gaps:133/355 - (37%)


- Green bases have known domain annotations that are detailed below.


Human   428 GHLFV---CVTLCE-------------QT-LEACLDVHRGED-----VENEE---DEFARNVLSS 467
            ||||.   |:.|.:             || |...|::..|.|     :::||   :|.|:...:.
 Frog    58 GHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMYDYIMKHEEGLSEELAKKYFAQ 122

Human   468 IFKAV---QELHLSCGYTHQDLQPQNILIDSKKA-AHLADFDKSIKW------------------ 510
            |..|:   .:||:    .|:||:|:|::...|:. ..|.||..|.|:                  
 Frog   123 IVHAISYCHKLHV----VHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAP 183

Human   511 ---AGDPQEVKR-DLEDLGRLVLYVVKKGSISFEDLKAQSNEEVVQLSP---------DEETKDL 562
               .||..:... |:..|| ::|:::..|:..|::  |..:|.:..:..         .::.|||
 Frog   184 EILLGDEYDAPAVDIWSLG-VILFMLVCGTPPFQE--ANDSETLTMIMDCKYTVPKHVSKDCKDL 245

Human   563 IHRLFHPGEHVRDCLSDLLGHPFFWTWESRYRTLRNVGNESDIKTRKSESEILRLLQPGPSEHSK 627
            |.|:.......|..|.::..||    |                         |:.:.|.|:    
 Frog   246 ITRMLQRDPKRRASLEEIENHP----W-------------------------L
QGVDPSPA---- 277

Human   628 SFDKWTTKINECVMKKMNKFYEKRGNFYQNTV-GDLLK--------------------FIRNLGE 671
                  ||.|..::...|...|:..:..|..| ||:..                    |:  |.|
 Frog   278 ------TKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVDALETNKYNHITATYFL--LAE 334

Human   672 HIDEEK-HKKMKLKIGDPS---LYFQKTFP 697
            .|..|| .|:.:.:...||   ..|::::|
 Frog   335 RILREKQEKETQTRSASPSNIKAQFRQSWP 364

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
ANK repeat 24..56 CDD:293786
ANK 1 24..53
Ank_2 29..122 CDD:289560
ANK 2 58..87
ANK 59..188 CDD:238125
ANK repeat 59..89 CDD:293786
ANK repeat 91..122 CDD:293786
ANK 3 91..120
Ank_2 96..199 CDD:289560
ANK repeat 124..154 CDD:293786
ANK 4 124..153
ANK repeat 167..199 CDD:293786
ANK 5 167..197
Ank_2 172..270 CDD:289560
ANK 196..321 CDD:238125
ANK repeat 201..236 CDD:293786
ANK 6 201..234
2-5A binding (P-loop) 1 229..242
ANK 7 238..268
Ank_2 243..326 CDD:289560
2-5A binding (P-loop) 2 253..275
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357 50/218 (23%)
Pkinase 387..586 CDD:278497 50/217 (23%)
RNase_RNase-L 590..708 CDD:199218 23/133 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
snrkNP_001123824.1 STKc_SNRK 12..269 CDD:270976 51/246 (21%)
S_TKc 16..269 CDD:214567 51/246 (21%)
UBA_SNRK 288..335 CDD:270524 8/48 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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