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Protein Alignment RNASEL and trpa1

DIOPT Version :9

Sequence 1:	NP_066956.1	Gene:	RNASEL / 6041	HGNCID:	10050	Length:	741	Species:	Homo sapiens
Sequence 2:	NP_001121434.1	Gene:	trpa1 / 100158526	XenbaseID:	XB-GENE-1004945	Length:	1144	Species:	Xenopus tropicalis

Alignment Length:	553	Identity:	122/553 - (22%)
Similarity:	203/553 - (36%)	Gaps:	151/553 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    20 RAAVEDNHLLIKAVQNEDVDLVQQ----------------------LLEGGA--------NVNFQ 54
            :|..:|||..:..:......|.:|                      :|:.|.        ::||.
Frog   177 QACCKDNHEALNLLLGRGAKLCKQNKLGCYPIHMTAFMGSLKCMDIILKKGEEMGYTIDHHINFT 241

Human    55 EEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVN 119
            ..|.. :|||.|||....|:|:..:.:||...||:.:.||....||..|:.:::|..:|..:|.|
Frog   242 NNEKS-SPLHLAVQNGNIDVVKACISYGAKIDLRQSDNATALHFAATQGATEIVKFMVSSYSDDN 305

Human   120 EC----DFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGH 180
            :.    |....|...::.::..|:..::|...|||::     .||:|     ..|.|:.|.....
Frog   306 KIVDLPDGNDETPLHKSVLFDHVELAEYLISEGANID-----SEDKE-----SRTPLLLATSCSA 360

Human   181 VEVLKILLDEMGADVNACDNMGRNALIHAL---------LSSD------------DSDVEAIT-- 222
            .:.:.:||.: ||||...|:.||| .:|.:         |:|:            |.|.|..|
Frog   361 WKSVNLLLSK-GADVKLKDHYGRN-FLHLMVLQPGGLKNLNSEFLQMENIKKLVSDEDCEGCTPL 423

Human   223 HLLLDHGADVNV------------RGERGKTPLILAVEKKHLGLVQRLLE--QEHIEINDTDSDG 273
            |....||...:|            :.:..::||..|.........||||.  .:...:||.|..|
Frog   424 HYACRHGVPNSVNNLLGLNMSLYSKSKNKRSPLHFAACYGRFNTCQRLLRFMSDGRLLNDGDEKG 488

Human   274 KTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRNYD--H--------SLVKVLLSHGA--- 325
            .|.|.||.|...:||..||.||||      |:::..|.:.  |        ..:|.||....
Frog   489 MTPLHLAAENGHEKIVFLLLKRGA------LLLSDHRGWTALHYAALSGYTRTIKTLLETSIGLI 547

Human   326 -KEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIY----LGFYE 385
             |.|        |.|::....|.::.|      ...:...::....|...:.|..|    :.|.:
Frog   548 DKTD--------KEQNTAMHLAGREGH------AKAVSLLLENGASILLNANGASYIHEAIRFGK 598

Human   386 KQEVAVKTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVHRG 450
            |..|.|.               :||.|....|.||..:.|::..:...:....::.:..||....
Frog   599 KDTVLVS---------------IQSERWEEILQTFSHTSSYKCAILEMIYHLPESFKTLLDRCMT 648

Human   451 EDVENEEDEFARNVLSSIFKAVQELHLSCGYTH 483
            |.:.:              |...:.|:...:|:
Frog   649 ESIGD--------------KKSPDFHVEYNFTY 667

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.