back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BCL6 and CG10321

DIOPT Version :10

Sequence 1:	NP_001697.2	Gene:	BCL6 / 604	HGNCID:	1001	Length:	706	Species:	Homo sapiens
Sequence 2:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	68/289 - (23%)
Similarity:	102/289 - (35%)	Gaps:	52/289 - (17%)

- Green bases have known domain annotations that are detailed below.

Human   425 LQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGSQSPQHAEMC 489
            |..|| ::.|....|..:|.|.|:.:...:|..|                   |..|.|
  Fly   530 LVGPT-MTVSSASPTPKRAKRSNHQIPAGVTLEP-------------------CDHQPP------ 568

Human   490 LHTAGPTFPEEMGETQS----EYSDSSCENGAFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDR 550
              .||.|...::....|    :.:......||....|.|.....| .:::||....|.: |.|..
  Fly   569 --AAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTE-FIRQHTSPLGSGR-YICHL 629

Human   551 CQASFRYKGNLASHKTVHTG------EKPYRCNICGAQFNRPANLKTHTRIHSGEKPY-KCETCG 608
            |...||....|.:|...||.      :|..:|.||...|..|..|:.|.:.|..|... .|..|.
  Fly   630 CSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPMCTICN 694

Human   609 ARFVQVAHLRAHVLIHTGEKPYPCEI--CGTRFRHLQTLKSHL-RIH--TGEKPYHCEKCNLHFR 668
            ..|...|.|..|...|. ::.|.|.:  |...|.....||.|: |.|  ..:..:.|.:|...:.
  Fly   695 RTFKSKAILYRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKCGECGSLYD 758

Human   669 HKSQLRLHLRQKHGAITNTKVQYRVSATD 697
            :...|:||:..     |:...:.::|..|
  Fly   759 NVDSLQLHVES-----TDHSAEVQISGQD 782

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.