DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Birc2 and Bruce

DIOPT Version :9

Sequence 1:	NP_068520.2	Gene:	Birc2 / 60371	RGDID:	620690	Length:	589	Species:	Rattus norvegicus
Sequence 2:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster

Alignment Length:	175	Identity:	53/175 - (30%)
Similarity:	73/175 - (41%)	Gaps:	30/175 - (17%)

- Green bases have known domain annotations that are detailed below.

  Rat   125 IHSSLPSNPLNSRAVEDFSLRM-NPCSYAMSTEEARFLSYSMWP---LSFLSPAELAKAGFYY-- 183
            |:..|....:.|| |.||.... |.....|.:|..|..::..||   ..:..|.::|:||||:
  Fly   217 INERLTDMMMGSR-VPDFGWNFSNFQRVLMHSEAVRRQTFEKWPHMDYKWALPDQMAQAGFYHQP 280

  Rat   184 -TGPGDRVACFACGGKLSNWEPNDDPLSEHRRHFPHCPFLENTSETQRFSVSNLSMQTHSARMRT 247
             :...||..||.|...|..||..|:|.|||.||.|.|||::. ..||...:|
  Fly   281 SSSGEDRAMCFTCSVCLVCWEKTDEPWSEHERHSPLCPFVKG-EYTQNVPLS------------- 331

  Rat   248 FLYWPSSVLVQPEQLASAGFYYVDHND--DVKCFCCD--GGLRCW 288
            ..|..:..|..|    ..||..:.::|  :|.|..|.  |.|..|
  Fly   332 ITYATNPALPAP----GLGFDIISNSDYANVLCTSCSQTGELSVW 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Birc2	NP_068520.2	BIR	24..93	CDD:197595
		BIR	155..224	CDD:197595	29/74 (39%)
		BIR	240..308	CDD:197595	12/53 (23%)
		UBA_BIRC2_3	362..408	CDD:270577
		CARD_BIRC2_BIRC3	425..514	CDD:260038
		zf-C3HC4_3	538..583	CDD:290631
Bruce	NP_001262460.1	BIR	251..321	CDD:279047	28/69 (41%)
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810