Protein Alignment RIT1 and Rgk2

DIOPT Version :10

• Sequence 1: NP_001243750.1
• Gene: RIT1 / 6016
• HGNCID: 10023
• Length: 236
• Species: Homo sapiens
• Sequence 2: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Alignment Length: 222
• Identity: 65/222 - (29%)
• Similarity: 109/222 - (49%)
• Gaps: 36/222 - (16%)

Human    26 GSCCSSPAGLSR--------------------EYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPT 70
            ||||.  ||.:.                    .|::||||..||||:|:..||::..:...:|.:
  Fly   496 GSCCG--AGYANVDSLPATPDDSENLDPPPPARYRVVMLGDAGVGKTALVNQFMTSEYMHTYDAS 558

Human    71 --IEDAY---KIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVRE 130
              ::|.:   .:.:.:|||.:::..:|.. ..|.:...........|.::.:|:.||.||....|
  Fly   559 LVLDDEFGEKTVSVLLDDEESDMVFIDHP-SVEMSVENSLSTYEPHGCVVVFSVVDRSSFRVAEE 622

Human   131 FKQLIYRVRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHAL 195
            ....:::...|.|..|:|||||:||.:.|.:|.:||.|||......|.|||:..::.:|::...:
  Fly   623 IINYLWQENYTKDKAVILVGNKADLARARLITSQEGKALAASRDAKFIETSSGIQHNVDELLVGI 687

Human   196 VREIRRKEKEAVLAMEKK---SKPKNS 219
            ::::|.|||.     |||   ||.|.|
  Fly   688 LKQMRLKEKR-----EKKATASKMKTS 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RIT1	NP_001243750.1	Rit_Rin_Ric	37..208	CDD:206712	52/195 (27%)
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	59/189 (31%)