| Sequence 1: | NP_000530.1 | Gene: | RHO / 6010 | HGNCID: | 10012 | Length: | 348 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_571159.1 | Gene: | rho / 30295 | ZFINID: | ZDB-GENE-990415-271 | Length: | 354 | Species: | Danio rerio |
| Alignment Length: | 347 | Identity: | 276/347 - (79%) |
|---|---|---|---|
| Similarity: | 312/347 - (89%) | Gaps: | 1/347 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQH 65
Human 66 KKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVV 130
Human 131 LAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLK 195
Human 196 PEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIA 260
Human 261 FLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGK 325
Human 326 NPLGDDE-ASATVSKTETSQVA 346 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RHO | NP_000530.1 | Rhodopsin_N | 3..37 | CDD:313611 | 28/33 (85%) |
| 7tmA_MWS_opsin | 38..317 | CDD:381742 | 226/278 (81%) | ||
| TM helix 1 | 40..64 | CDD:381742 | 18/23 (78%) | ||
| TM helix 2 | 73..95 | CDD:381742 | 18/21 (86%) | ||
| TM helix 3 | 111..133 | CDD:381742 | 18/21 (86%) | ||
| 'Ionic lock' involved in activated form stabilization. /evidence=ECO:0000305|PubMed:26200343 | 134..136 | 1/1 (100%) | |||
| TM helix 4 | 155..171 | CDD:381742 | 12/15 (80%) | ||
| TM helix 5 | 201..224 | CDD:381742 | 18/22 (82%) | ||
| TM helix 6 | 251..273 | CDD:381742 | 19/21 (90%) | ||
| TM helix 7 | 285..310 | CDD:381742 | 17/24 (71%) | ||
| Interaction with SAG. /evidence=ECO:0000269|PubMed:26200343, ECO:0000269|PubMed:28753425 | 330..348 | 10/18 (56%) | |||
| rho | NP_571159.1 | Rhodopsin_N | 2..37 | CDD:287397 | 29/34 (85%) |
| 7tm_4 | 45..323 | CDD:304433 | 226/277 (82%) | ||
| 7tm_1 | 55..306 | CDD:278431 | 207/250 (83%) | ||
| 'Ionic lock' involved in activated form stabilization. /evidence=ECO:0000250|UniProtKB:P02699 | 134..136 | 1/1 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 333..354 | 9/15 (60%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C194331424 | |
| Domainoid | 1 | 1.000 | 457 | 1.000 | Domainoid score | I3442 |
| eggNOG | 1 | 0.900 | - | - | E33208_3B9M9 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 604 | 1.000 | Inparanoid score | I5214 |
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG40455 | |
| OrthoDB | 1 | 1.010 | - | - | D265234at7742 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0004010 | |
| OrthoInspector | 1 | 1.000 | - | - | oto47417 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_110730 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24240 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R6203 |
| SonicParanoid | 1 | 1.000 | - | - | X120 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 1 | 1.500 | - | - | ||
| 16 | 16.300 | |||||