Protein Alignment RHEB and Rap2l

DIOPT Version :10

• Sequence 1: NP_005605.1
• Gene: RHEB / 6009
• HGNCID: 10011
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_477402.1
• Gene: Rap2l / 37850
• FlyBaseID: FBgn0283666
• Length: 182
• Species: Drosophila melanogaster
• Alignment Length: 159
• Identity: 62/159 - (38%)
• Similarity: 101/159 - (63%)
• Gaps: 0/159 - (0%)

Human     8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQ 72
            |:.:||...||||:||:|||.|.|::.||||||:.:.|.|.|:.....|:::||||.::::....
  Fly     5 KVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFASMRD 69

Human    73 TYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKAL 137
            .|..:.:|:|::||:|:.::|:.|..:...:..:.|....||:||.||.||..:|.:|..||.||
  Fly    70 LYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAEGNAL 134

Human   138 AESWNAAFLESSAKENQTAVDVFRRIILE 166
            |:.|:..|:|:|||:.....:||..|:.|
  Fly   135 AQLWDCPFIEASAKDRINVNEVFATIVRE 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHEB	NP_005605.1	RheB	6..184	CDD:206709	62/159 (39%)
		Effector region. /evidence=ECO:0000305	35..43		6/7 (86%)
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	57/148 (39%)