DRSC/TRiP Functional Genomics Resources

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Protein Alignment RHEB and Rheb

DIOPT Version :9

Sequence 1:NP_005605.1 Gene:RHEB / 6009 HGNCID:10011 Length:184 Species:Homo sapiens
Sequence 2:NP_730950.2 Gene:Rheb / 117332 FlyBaseID:FBgn0041191 Length:182 Species:Drosophila melanogaster


Alignment Length:183 Identity:117/183 - (63%)
Similarity:148/183 - (80%) Gaps:2/183 - (1%)


- Green bases have known domain annotations that are detailed below.


Human     1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQD 65
            || :|.|.||::||||||||||.||||||||||||||||||||||:..|..|:|.::|:||||||
  Fly     1 MP-TKERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQD 64

Human    66 EYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVIS 130
            ||||||..||:|.:||:||||:||.|||||:|:|:.||||::||..:|::|||||.|||.||.:|
  Fly    65 EYSIFPVQYSMDYHGYVLVYSITSQKSFEVVKIIYEKLLDVMGKKYVPVVLVGNKIDLHQERTVS 129

Human   131 YEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSV 183
            .||||.|||||.|||||:|||:|::..|:|.::::..|..:| ..|.||.|.|
  Fly   130 TEEGKKLAESWRAAFLETSAKQNESVGDIFHQLLILIENENG-NPQEKSGCLV 181

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RHEBNP_005605.1 RheB 6..184 CDD:206709 114/178 (64%)
Effector region. /evidence=ECO:0000305 35..43 7/7 (100%)
RhebNP_730950.2 RheB 5..182 CDD:206709 114/178 (64%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 225 1.000 Domainoid score I2543
eggNOG 1 0.900 - - E2759_KOG0395
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 235 1.000 Inparanoid score I3406
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1320427at2759
OrthoFinder 1 1.000 - - FOG0002658
OrthoInspector 1 1.000 - - oto90267
orthoMCL 1 0.900 - - OOG6_104157
Panther 1 1.100 - - LDO PTHR24070
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1095
SonicParanoid 1 1.000 - - X2033
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1413.860

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