Protein Alignment RFC5 and RfC4

DIOPT Version :10

• Sequence 1: NP_031396.1
• Gene: RFC5 / 5985
• HGNCID: 9973
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_523915.1
• Gene: RfC4 / 38492
• FlyBaseID: FBgn0260985
• Length: 331
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 116/322 - (36%)
• Similarity: 187/322 - (58%)
• Gaps: 3/322 - (0%)

Human     7 KQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71
            ::.|:.|..|..:|||:|||||....:::.::|.::.:..|..:...|::::.||||.|||:||.
  Fly     3 EEPEKTADDKRSHLPWIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQ 67

Human    72 ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQ 135
            ..|:.|..| .:...|||||||::||||::|..|..||..:....:| .|:|||||||:||:.||
  Fly    68 CLARILLGD-SYKEAVLELNASNERGIDVVRNKIKMFAQQKVTLPRGRHKIVILDEADSMTEGAQ 131

Human   136 NALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISED 200
            .||||.:|.::..|||.|.||...|||..:||||...||..|:...::.:|..|.:.||::.:||
  Fly   132 QALRRTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTED 196

Human   201 GMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 265
            |::|:|..:.||||:.||.||||...||.:|.|.|:.....|....:..::......|...||:.
  Fly   197 GLEAIVFTAQGDMRQGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDIHKAYKI 261

Human   266 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIA 327
            :.:|..| |.:..||:..|.....|::....:::..:.::.....::..|.|..:||::|:|
  Fly   262 LAKLWKL-GYSPEDIIANIFRVCKRINIDEHLKLDFIREIGITHMKIIDGINSLLQLTALLA 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RFC5	NP_031396.1	rfc	16..329	CDD:234763	114/313 (36%)
RfC4	NP_523915.1	PLN03025	16..330	CDD:178596	113/309 (37%)