Protein Alignment RFC5 and CG8142

DIOPT Version :10

• Sequence 1: NP_031396.1
• Gene: RFC5 / 5985
• HGNCID: 9973
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_573245.1
• Gene: CG8142 / 32763
• FlyBaseID: FBgn0030871
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 335
• Identity: 122/335 - (36%)
• Similarity: 197/335 - (58%)
• Gaps: 23/335 - (6%)

Human     7 KQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71
            |.|..|||.:....||||||||:.::|::...::::.::|.:....||::|||||||||||||||
  Fly    17 KSQGTPAARRKPPAPWVEKYRPRNVDDVVEQSEVVAVLRKCVEGGDLPNMLLYGPPGTGKTSTIL 81

Human    72 ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFA--STRTIFKKG-----FKLVILDEADA 129
            |.::|::.|. |...:|||||||:|||:::|..|.:|:  |..::...|     ||::||||||:
  Fly    82 AASRQIFGDM-FKDRILELNASDERGINVVRTKIKNFSQLSASSVRPDGKPCPPFKIIILDEADS 145

Human   130 MTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEK 194
            ||..||:||||.:||.:.:|||||||||:|:||..:.|||::|||..|..:.::.||:::.|.|.
  Fly   146 MTHAAQSALRRTMEKESRSTRFCLICNYVSRIIVPITSRCSKFRFKALGEDKVIDRLKYICEMEG 210

Human   195 VDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDF 259
            |.|.:|..|::|.:|.||:|||:..|||.....|  .|..:.|..    ..:::.::.....:|:
  Fly   211 VKIEDDAYKSIVKISGGDLRRAITTLQSCYRLKG--PEHIINTAD----LFEMSGVIPEYYLEDY 269

Human   260 TTA-----YRNITELKTLKGLALHDI--LTE--IHLFVHRVDFPSSVRIHLLTKMADIEYRLSVG 315
            ...     |..:.:.....|.:.:.:  :.|  :...||........:..:..|:.:..:||..|
  Fly   270 LEVCRSGNYERLEQFVREIGFSAYSVGQMMEQFVEFIVHHPGLNDPQKATICDKLGECCFRLQDG 334

Human   316 TNEKIQLSSL 325
            .:|.:|:..|
  Fly   335 GSEYLQIMDL 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RFC5	NP_031396.1	rfc	16..329	CDD:234763	117/326 (36%)
CG8142	NP_573245.1	rfc	31..344	CDD:234763	116/319 (36%)