Sequence 1: | NP_066124.1 | Gene: | RET / 5979 | HGNCID: | 9967 | Length: | 1114 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001014583.1 | Gene: | btl / 39564 | FlyBaseID: | FBgn0285896 | Length: | 1052 | Species: | Drosophila melanogaster |
Alignment Length: | 752 | Identity: | 227/752 - (30%) |
---|---|---|---|
Similarity: | 323/752 - (42%) | Gaps: | 181/752 - (24%) |
- Green bases have known domain annotations that are detailed below.
Human 377 NDSDFQGP------GAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSG 435
Human 436 INVQYKLHSSGANCS---------TLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQ 491
Human 492 TSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFS 556
Human 557 TCSPSTKTCPDGHCDVVETQDINICPQD-------------------CLRGSIVGGHEPGEPRGI 602
Human 603 KAGYGTCNC---------FPEEEKCFCEPEDI-----QDPLCDELCRTVIAAAVLF--SFIVSVL 651
Human 652 -------LSAFCIHCYHKFAHKPPI-----------SSAEM---TFRRPAQAFPVSYSSSGARRP 695
Human 696 SLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL--KGRAGYTTVAVK 758
Human 759 MLKENASPSELRDLLSEFNVLKQV-NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKV 822
Human 823 GP-------GYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNI 880
Human 881 LVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIV 945
Human 946 TLGGNPYPGI-PPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1009
Human 1010 VKRRD-----YLDLA---ASTPSDSLIYDDGLSEEET 1038 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RET | NP_066124.1 | Cadherin | 172..261 | CDD:278457 | |
PTKc_RET | 723..1012 | CDD:173631 | 137/299 (46%) | ||
Pkinase_Tyr | 724..1005 | CDD:285015 | 137/291 (47%) | ||
Inhibitors binding | 805..807 | 1/1 (100%) | |||
btl | NP_001014583.1 | IG_like | 149..232 | CDD:214653 | |
IGc2 | 157..215 | CDD:197706 | |||
IG | 247..336 | CDD:214652 | |||
Ig | 258..340 | CDD:143165 | |||
I-set | 394..479 | CDD:254352 | 16/106 (15%) | ||
IGc2 | 408..469 | CDD:197706 | 11/82 (13%) | ||
IG_like | 492..583 | CDD:214653 | 20/131 (15%) | ||
Ig | 507..583 | CDD:299845 | 19/116 (16%) | ||
PKc_like | 700..1000 | CDD:304357 | 142/314 (45%) | ||
TyrKc | 712..996 | CDD:197581 | 137/291 (47%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |