Sequence 1: | NP_066124.1 | Gene: | RET / 5979 | HGNCID: | 9967 | Length: | 1114 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_608762.3 | Gene: | CG3277 / 33543 | FlyBaseID: | FBgn0031518 | Length: | 789 | Species: | Drosophila melanogaster |
Alignment Length: | 799 | Identity: | 199/799 - (24%) |
---|---|---|---|
Similarity: | 331/799 - (41%) | Gaps: | 229/799 - (28%) |
- Green bases have known domain annotations that are detailed below.
Human 358 LNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLP------------------VSLHL 404
Human 405 PSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGA----------------NCS--- 450
Human 451 --------TLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGS 507
Human 508 YVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDV 572
Human 573 VE--------------TQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPE 623
Human 624 DIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYS 688
Human 689 SSGARRPSLDSMENQVS-VDAFKILEDPK-------WEFPRKNLVLGKTLGEGEFGKVVKATAFH 745
Human 746 LKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV-NHPHVIKLYGACSQDGPLLLIVEYAKY 809
Human 810 GSLRGFLRESRKV-------GPGY---------LGSGGSRNSSSLD------------------- 839
Human 840 ---------HP-----------DERA----LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNI 880
Human 881 LVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIV 945
Human 946 TLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMV 1010
Human 1011 KRRDYLDLAASTPSDSLIY 1029 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RET | NP_066124.1 | Cadherin | 172..261 | CDD:278457 | |
PTKc_RET | 723..1012 | CDD:173631 | 123/348 (35%) | ||
Pkinase_Tyr | 724..1005 | CDD:285015 | 121/340 (36%) | ||
Inhibitors binding | 805..807 | 1/1 (100%) | |||
CG3277 | NP_608762.3 | STYKc | 426..763 | CDD:214568 | 123/344 (36%) |
PTKc | 430..763 | CDD:270623 | 122/340 (36%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |