Sequence 1: | NP_066124.1 | Gene: | RET / 5979 | HGNCID: | 9967 | Length: | 1114 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_733018.1 | Gene: | Wsck / 318600 | FlyBaseID: | FBgn0046685 | Length: | 791 | Species: | Drosophila melanogaster |
Alignment Length: | 801 | Identity: | 179/801 - (22%) |
---|---|---|---|
Similarity: | 301/801 - (37%) | Gaps: | 190/801 - (23%) |
- Green bases have known domain annotations that are detailed below.
Human 282 VVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLL---PGDTWAQQTFRVEHWPNETSVQAN 343
Human 344 GSFVRATVHDYRLVL---------NRNLSISENRTMQLAVLVNDSDFQG-PGAGVLLLHFNVSVL 398
Human 399 PVSLHLPSTYSLSVSRRARRFAQIGKVCVENC-QAF----------SGINVQYKLHSSGANCSTL 452
Human 453 GVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSY-VAEEAGCP 516
Human 517 LSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDV----VETQD 577
Human 578 INICPQDCLRGSIVGGHEPGEPRGI-KAGY--GTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIA 639
Human 640 AAVLFSFIVSVLLSAFCIHCYHKF------------AHKPPISSAEMTFRRP----------AQA 682
Human 683 FPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVL--GKTLGEGEFGKVVKATAFH 745
Human 746 LKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV-NHPHVIKLYGACSQDGPLLLIVEYAKY 809
Human 810 GSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRD 874
Human 875 LAARNILVAEGRKMKISDFG------LSRDVYEEDSYVKRSQGRIPVKWMAIESL-FDHIYTTQS 932
Human 933 DVWSFGVLLWEIVTLGGNPYPG--IPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKR 995
Human 996 PVFADISKDLEKMMVKRRDYL 1016 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RET | NP_066124.1 | Cadherin | 172..261 | CDD:278457 | |
PTKc_RET | 723..1012 | CDD:173631 | 75/300 (25%) | ||
Pkinase_Tyr | 724..1005 | CDD:285015 | 74/292 (25%) | ||
Inhibitors binding | 805..807 | 1/1 (100%) | |||
Wsck | NP_733018.1 | WSC | 42..115 | CDD:280068 | 4/25 (16%) |
fn3 | 130..222 | CDD:278470 | 20/104 (19%) | ||
TyrKc | 493..746 | CDD:197581 | 72/282 (26%) | ||
PTKc | 497..750 | CDD:270623 | 71/282 (25%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |