DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DPF2 and SFP1

DIOPT Version :9

Sequence 1:	XP_024304405.1	Gene:	DPF2 / 5977	HGNCID:	9964	Length:	575	Species:	Homo sapiens
Sequence 2:	NP_013507.1	Gene:	SFP1 / 851119	SGDID:	S000004395	Length:	683	Species:	Saccharomyces cerevisiae

Alignment Length:	314	Identity:	63/314 - (20%)
Similarity:	85/314 - (27%)	Gaps:	156/314 - (49%)

- Green bases have known domain annotations that are detailed below.

Human   138 VDDDSLGEF----------PVTNS------------RARKRILEPDDF-----LDDLDDEDYEED 175
            :|||.||..          |.|.|            ::.:.::|..|.     .||:||:|.::|
Yeast   488 MDDDILGPSNHNSMNSVVNPTTGSHNYNTFHSSVHAKSSQNMVEDQDIDDIDDDDDVDDDDDDDD 552

Human   176 TPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDSECLTSGWVDLALDPAPALDMRGGRVVF 240
            .........|.||.|.:...|:.                  ...::|   |||        |.::
Yeast   553 DDDTENGSSSNGKSVHNNNYKMP------------------QQAYID---DPA--------RRLY 588

Human   241 LPRVLKQTWALVLPADCFRLRPLGGLGPCYMTGGTCMLWERFLPSSGVGLLVGATAGRVGLSTDG 305
            :....:|.     |..|    |:.|....|....              ||......|...
Yeast   589 VMDHEEQK-----PFKC----PVIGCEKTYKNQN--------------GLKYHRLHGHQN----- 625

Human   306 LQVSWPQLSQGPRGLTLSFSTSVLFFFLSALPHFCPSTLGAPSPLGFLSRLLCFPAAAAPVSSVS 370
                 .:|.:.|.|                                              ..||.
Yeast   626 -----QKLHENPDG----------------------------------------------TFSVI 639

Human   371 RPSSHDFSFCLSDSF-------KQKHTSKAPQR--VCGKRYKNRPGLSYHYAHS 415
            .|.|       :|||       |.|     |.|  ||||||||..||.||..||
Yeast   640 DPDS-------TDSFGDGMGSAKDK-----PYRCEVCGKRYKNLNGLKYHRGHS 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPF2	XP_024304405.1	Requiem_N	13..79	CDD:316564
		SFP1	<397..417	CDD:227516	14/19 (74%)
		PHD1_DPF2_like	456..511	CDD:277161
		PHD2_d4	513..558	CDD:277005
SFP1	NP_013507.1	SFP1	43..683	CDD:227516	63/314 (20%)
		C2H2 Zn finger	600..629	CDD:275368	7/56 (13%)
		C2H2 Zn finger	661..683	CDD:275368	14/21 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3744
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950