Protein Alignment DPF2 and d4

DIOPT Version :10

• Sequence 1: NP_001317237.1
• Gene: DPF2 / 5977
• HGNCID: 9964
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_610163.1
• Gene: d4 / 35485
• FlyBaseID: FBgn0033015
• Length: 497
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 178/491 - (36%)
• Similarity: 235/491 - (47%)
• Gaps: 124/491 - (25%)

Human     6 ENVVKLLGE-QYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKRHRGPGLASG 69
            |.:...|.: :.||:.:|...|:|.|||.||.:|:||||.||||||::|.::|:|:.|.|||..|
  Fly    19 EKIQNFLNDKEKYKEILENSENFNTRLCIERRLRMPFLDPQTGVAQTHCSLFMKKKQRMPGLRHG 83

Human    70 QLYSYPARRWRKKRRAHPPEDPRLSF-------PSIKPDTDQTLKKEGLISQDGSSLEALLRTDP 127
            |:|:||:.||||.:|.: ..:|..||       .:::....||.:....|...|.::.    .:|
  Fly    84 QIYTYPSSRWRKPKRQY-LLNPNQSFRAYQYREHNLQHSHHQTHQHHHHIPSSGVAVP----QNP 143

Human   128 LEKRGAPDPRVDDDSLGEFPVTNSRARKRILEP---------------DDFLDDLD-DEDYEED- 175
            .....|.....|.:|:|.....:|:.....:|.               |:|.||.| |.|::|.
  Fly   144 HLAESAAIAATDGNSMGASGDNDSKDSHANVEKEWFHDEMDTSHFHHGDEFEDDFDSDNDFDESY 208

Human   176 ---------------------TPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDNSFKQKH 219
                                 ||||..||       |..|:|.......|| |..|..||   .:
  Fly   209 TSRGKRKKCSRPRRTNANVEGTPKRGRKG-------GGNRRKNAVEGESDR-KRRAGGNS---AN 262

Human   220 TSKA--------PQRVCGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQP----PTPVSQRSEEQK 272
            ||.|        ....|........||  :.:||:.|.....:.::||.    ||.:|...::..
  Fly   263 TSAAAAAAAAAVAHAACTAAAVASTGL--YASHSNSASPIPINDDNSQSGLILPTNISSSYDKTS 325

Human   273 SKKGPDG------------------------------------------------LALPNNYCDF 289
            |..|...                                                :|.|:.||||
  Fly   326 SDAGASNDSIPLATMVAINAGLTTSNVCNAHPVQTGTNQTVFATGNKVKQRVERDIAQPSPYCDF 390

Human   290 CLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDD 354
            ||||.:.||||..||||||||||||||||||||||..|:.:||.|||||||||.|:|||||:|||
  Fly   391 CLGDQRENKKTNMPEELVSCSDCGRSGHPSCLQFTANMIISVKRYRWQCIECKYCSICGTSDNDD 455

Human   355 QLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLD 390
            |||||||||||||||||:|.:..||||||||.||::
  Fly   456 QLLFCDDCDRGYHMYCLSPPLVTPPEGSWSCKLCME 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DPF2	NP_001317237.1	DPF1-3_N	13..75	CDD:464074	31/62 (50%)
		SFP1	<201..247	CDD:227516	14/53 (26%)
		PHD1_DPF2_like	286..341	CDD:277161	43/54 (80%)
		PHD2_d4	343..388	CDD:277005	35/44 (80%)
d4	NP_610163.1	DPF1-3_N	31..93	CDD:464074	33/61 (54%)
		PHD1_d4	387..442	CDD:277091	43/54 (80%)
		PHD2_d4	444..489	CDD:277005	35/44 (80%)