| Sequence 1: | NP_001391586.1 | Gene: | RELA / 5970 | HGNCID: | 9955 | Length: | 562 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_477094.1 | Gene: | Rel / 41087 | FlyBaseID: | FBgn0014018 | Length: | 971 | Species: | Drosophila melanogaster |
| Alignment Length: | 396 | Identity: | 125/396 - (31%) |
|---|---|---|---|
| Similarity: | 180/396 - (45%) | Gaps: | 74/396 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MDELFPLIFPA--EPAQASG---------------PYVEIIEQPKQRGMRFRYKCEGRSA-GSIP 47
Human 48 GERSTDTTKTHPTIKVWMSGPLYFGQINGYTGPGTVRISLVTKDPPHRPHPHEL-VGKDCRDGFY 111
Human 112 EAELCPDRCIH---------SFQNLGI-----------QCVKKRDLEQAISQRIQTNNNPFQ--- 153
Human 154 VPIEEQRGDYDLNAVRLCFQVTVRDPSGR--PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGS 216
Human 217 CLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQADVHRQVAIVFRTPPYADPSLQA 275
Human 276 PVRVSMQLRRPSDRELSEP-MEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPP 339
Human 340 RRIAVP 345 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RELA | NP_001391586.1 | RHD-n_RelA | 19..198 | CDD:143645 | 63/205 (31%) |
| IPT_NFkappaB | 205..301 | CDD:238582 | 43/102 (42%) | ||
| Nuclear localization signal. /evidence=ECO:0000255 | 312..315 | 2/2 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 320..359 | 5/26 (19%) | |||
| Transcriptional activation domain 3. /evidence=ECO:0000250|UniProtKB:Q04207 | 353..400 | ||||
| Transcriptional activation domain 1. /evidence=ECO:0000269|PubMed:1732726 | 426..487 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 517..541 | ||||
| Transcriptional activation domain 2. /evidence=ECO:0000250|UniProtKB:Q04207 | 531..562 | ||||
| 9aaTAD. /evidence=ECO:0000255 | 547..555 | ||||
| Rel | NP_477094.1 | RHD-n_Relish | 150..336 | CDD:143644 | 63/205 (31%) |
| IPT_NFkappaB | 343..446 | CDD:238582 | 43/102 (42%) | ||
| ANKYR | 590..805 | CDD:440430 | |||
| ANK repeat | 640..671 | CDD:293786 | |||
| ANK repeat | 673..708 | CDD:293786 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||