Protein Alignment atp8b1 and DRS2

DIOPT Version :9

• Sequence 1: NP_001025562.1
• Gene: atp8b1 / 594952
• XenbaseID: XB-GENE-490143
• Length: 1250
• Species: Xenopus tropicalis
• Sequence 2: NP_009376.2
• Gene: DRS2 / 851207
• SGDID: S000000024
• Length: 1355
• Species: Saccharomyces cerevisiae
• Alignment Length: 1237
• Identity: 468/1237 - (37%)
• Similarity: 685/1237 - (55%)
• Gaps: 151/1237 - (12%)

 Frog    28 TDDELDSPQTDEPEQNRRNVQ--------------AEQSREPVIKECTWQVKANDRNFYDQPEFK 78
            |::|||....|  .:|:.|::              ||.:.||.:      :..||.
Yeast   143 TNNELDDNYLD--SRNKFNIKILFNRYILRKNVGDAEGNGEPRV------IHINDS--------- 190

 Frog    79 KKVFLCLKKSKYAGNAIKTYKYNPITFLPVNLYEQFKRAANAYFLVLLILQTIPQISTVTWSTTL 143
                |......|:.|.|.|.|||..||||..|:::|.:.||.:||....:|.:|.:|.....||:
Yeast   191 ----LANSSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTI 251

 Frog   144 IPLLLVLGITAIKDLVDDIARHKMDNEINNRPSEVITDGR--FKKTKWKHIHVGDIIRINKNEFV 206
            ..||:||.::|:|:.::||.|...|.|:||..:|:.::..  |.:.:|..|.||||||:...|.:
Yeast   252 GTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPI 316

 Frog   207 PADVLLLSSSDPNSLCYVETAELDGETNLKFKMSLEITDKLLQKEEQLAGFDGLVECEEPNNRLD 271
            |||.::||||:|..|||:|||.||||||||.|.|...|.|.:. .:.|...:|.|..|:||:.|.
Yeast   317 PADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFID-VKTLKNMNGKVVSEQPNSSLY 380

 Frog   272 KFVGTLFWRGNSFGLDADKILLRGCTVRNTEYCHGLVLFAGADTKIMRNSGKTRLKRTKIDYLMN 336
            .:.||:........|..|:::|||.|:|||.:..|||:|.|.:||::||:..|.:|||.::.::|
Yeast   381 TYEGTMTLNDRQIPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIIN 445

 Frog   337 YMVYTIFVLLILAAAGLAIGQTFWEAKLGAANVSWYLYDGNNYSP-SYRGFLAFWGYIIVLNTMV 400
            ..:..:|.:||:.....:||.... :...|.::|:...:|.|.:. .::.||.||   |:.:.:|
Yeast   446 RQIIALFTVLIVLILISSIGNVIM-STADAKHLSYLYLEGTNKAGLFFKDFLTFW---ILFSNLV 506

 Frog   401 PISLYVSVEVIRLGQSYFINWDLQMYFSPKDTPAKARTTTLNEQLGQIQYIFSDKTGTLTQNIMT 465
            ||||:|:||:|:..|::.|..||.:|:...|||...||::|.|:||||:|||||||||||:|||.
Yeast   507 PISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIME 571

 Frog   466 FKKCTINGTTYGDD---------DDELKSGQTKQVDFSWNPLADPSFTFHDNYLIEQIRAGKDKD 521
            ||.|:|.|..|.|.         :|.::.|..|..|.. ..|.|||                |:|
Yeast   572 FKSCSIAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLK-KKLNDPS----------------DED 619

 Frog   522 ---VYEFFKLLALCHTVMAE-KTDGELIYQAASPDEGALVTAARNFGFVFLSRTQSTITI--SEL 580
               :.:|..|||.||||:.| ::||.:.||||||||||||....:.|:.|:.|..:::|:  .|.
Yeast   620 SPIINDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEET 684

 Frog   581 GQEKTYEVLAILDFNSDRKRMSIIVRQPDGRIRLYCKGADTVIYERLHPD-NPIKDQTQKALDIF 644
            |:||.|::|.|.:|||.|||||.|.|.|||.|:|:||||||||.|||..: |...:.|.:.|:.:
Yeast   685 GEEKEYQLLNICEFNSTRKRMSAIFRFPDGSIKLFCKGADTVILERLDDEANQYVEATMRHLEDY 749

 Frog   645 ANASLRTLCLCYKDINKGDFENWSKKYKQASVATSNRDEALDRVYEAIETDLKLLGATAIEDKLQ 709
            |:..||||||..:||::|::|.|:..|.:|:....||.|.||.....||.:|.|:||||||||||
Yeast   750 ASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQ 814

 Frog   710 DDVSGTIFNLARADIKIWVLTGDKKETAENIGYSCKLLDDDTEILYGEDINVHLQTRMENQRNQM 774
            |.|..||..|..|.|||||||||::|||.|||.||:||.:|..:|.     ::.:||.:.:||.:
Yeast   815 DGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLI-----INEETRDDTERNLL 874

 Frog   775 SGNQGAQSNQSGAFLPTDKKH--ALIITGSWLNEILLEKKKRKKKRLKLKFPRTKEEKEQQLHEK 837
            ........:|    |.|...:  ||:|.|                                   |
Yeast   875 EKINALNEHQ----LSTHDMNTLALVIDG-----------------------------------K 900

 Frog   838 LKAYALKEQRQRSFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAVTLAIGDGANDVNMIKTA 902
            ...:||:.:.:...:.:|..|.|||||||:|.|||:||.:|||...::.||||||||||:||:.|
Yeast   901 SLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAA 965

 Frog   903 HIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFSFTLVHFWYS 967
            |:||||||.|||||..|:|.:..||::|::||||||.|||.|:...:.|.||||.:..:..|||.
Yeast   966 HVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYV 1030

 Frog   968 FFNGFSAQTVYEDWFITLYNVLYSSLPVLLVGLLDQDVSDKLSLAFPRLYVPGQKDLLFNYKKFF 1032
            |.|.||.|::.|.|.::.||:.::..|..::|:.||.||.:|...:|:||..|||...|:...|:
Yeast  1031 FANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFW 1095

 Frog  1033 LSLFHGIVTSLIIF-----FIPYGAFLLTMGQDGEAPSDYQSFAVTTATALVITVNFQIGLDTSY 1092
            ..:.:|...|.|:|     ...|| |.|.|  .||. :|:.|:.||..|..||.|..:..|.|:.
Yeast  1096 GWIINGFFHSAIVFIGTILIYRYG-FALNM--HGEL-ADHWSWGVTVYTTSVIIVLGKAALVTNQ 1156

 Frog  1093 WTFVNAFSIFGSIAIYFGIMFDLHSAGIHVLFPSMFI---FTGAAPNALRQPYLWLTIILTVAFC 1154
            ||.....:|.||: :::.|.|.::::    :||...|   :.|...:.......|||:|
Yeast  1157 WTKFTLIAIPGSL-LFWLIFFPIYAS----IFPHANISREYYGVVKHTYGSGVFWLTLI------ 1210

 Frog  1155 LLPIVAL--RFL---AKTIWPSESDKIQKKGKKFKAEVEQRAKPKPFARGVSTRRSAYAFSHQRG 1214
            :|||.||  .||   .|.::..|:..:.::.:|:... :.|...:.|...:...|.......|||
Yeast  1211 VLPIFALVRDFLWKYYKRMYEPETYHVIQEMQKYNIS-DSRPHVQQFQNAIRKVRQVQRMKKQRG 1274

 Frog  1215 YA 1216
            :|
Yeast  1275 FA 1276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atp8b1	NP_001025562.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		9/37 (24%)
		P-type_ATPase_APLT_Dnf-like	92..1049	CDD:319770	404/982 (41%)
DRS2	NP_009376.2	ATPase-Plipid	198..1240	CDD:273734	446/1122 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1713
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920