DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBMS2 and rbms2a

DIOPT Version :9

Sequence 1:	XP_006719604.1	Gene:	RBMS2 / 5939	HGNCID:	9909	Length:	477	Species:	Homo sapiens
Sequence 2:	XP_009304028.1	Gene:	rbms2a / 378458	ZFINID:	ZDB-GENE-030912-2	Length:	396	Species:	Danio rerio

Alignment Length:	356	Identity:	269/356 - (75%)
Similarity:	299/356 - (83%)	Gaps:	19/356 - (5%)

- Green bases have known domain annotations that are detailed below.

Human     1 MLLSVTSRPGISTF-GYN-RNNKK--PYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYIR 61
            |||||..|.|.:.: ||| ||.||  .|||.:||||     .|:|||||.|...:||||||||||
Zfish     1 MLLSVPPRTGFNPYSGYNSRNGKKQQAYVSSSQQMA-----LSSPNSSSSSIAGEQLSKTNLYIR 60

Human    62 GLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQM 126
            ||.|||||||||||||||||||||||||||||||||||||||||||:||||||||||::||||||
Zfish    61 GLHPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVTALKSTGVQAQM 125

Human   127 AKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAI 191
            |||||||||||||||||:||||||||.|||.||||||||||||.:||||||||||||||||||||
Zfish   126 AKQQEQDPTNLYISNLPVSMDEQELEAMLKSFGQVISTRILRDANGTSRGVGFARMESTEKCEAI 190

Human   192 ITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTA 256
            |.||||||||||||||.|::||||||||||.||||||.|::||||:|.|:||.|.|.||||| ||
Zfish   191 IQHFNGKYIKTPPGVPVPTEPLLCKFADGGQKKRQNQNKYLQNGRSWTRDADTGGMTLTYDP-TA 254

Human   257 LQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVL 321
            ||||||.:||:|.||||:||::||||:.|.|.||         |:.:||||||.||||||:|::|
Zfish   255 LQNGFYSSPYSIGPNRMIAQTSLSPYMPSQVPSY---------QMHSPSWMHHQSYLMQPTGALL 310

Human   322 TPGMDHPISLQPASMMGPLTQQLGHLSLSST 352
            |..:||.:|||.:||||||||||.||||.||
Zfish   311 TQALDHQMSLQSSSMMGPLTQQLSHLSLGST 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBMS2	XP_006719604.1	RRM1_MSSP1	49..134	CDD:240914	77/84 (92%)
RBMS2	XP_006719604.1	RRM2_MSSP2	135..220	CDD:240918	75/84 (89%)
rbms2a	XP_009304028.1	RRM_SF	50..133	CDD:302621	77/82 (94%)
rbms2a	XP_009304028.1	RRM2_MSSP2	134..219	CDD:240918	75/84 (89%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	271	1.000	Domainoid score	I8636
eggNOG	1	0.900	-	-		E1_KOG4733
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37706
Inparanoid	1	1.050	592	1.000	Inparanoid score	I5369
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG41051
OrthoDB	1	1.010	-	-		D252731at7742
OrthoFinder	1	1.000	-	-		FOG0001320
OrthoInspector	1	1.000	-	-		otm27121
orthoMCL	1	0.900	-	-		OOG6_110472
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3067
SonicParanoid	1	1.000	-	-		X530
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	17	17.370