Protein Alignment RBM4 and pAbp

DIOPT Version :9

• Sequence 1: NP_002887.2
• Gene: RBM4 / 5936
• HGNCID: 9901
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_476667.1
• Gene: pAbp / 37070
• FlyBaseID: FBgn0265297
• Length: 634
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 109/497 - (21%)
• Similarity: 162/497 - (32%)
• Gaps: 193/497 - (38%)

Human     4 LFIGNLPREATEQEIRSLFEQYGKVLECDII-------KNYGFVHIEDKTAAEDAIRNLHHYKLH 61
            :||.||.|....:.|...|..:|.:|.|.:.       |.|||||.|.:.||..:|..::...|:
  Fly    92 VFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGYGFVHFETEEAANTSIDKVNGMLLN 156

Human    62 GVNINV-------EASK---NKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIV------ 110
            |..:.|       |..|   .|:|..|.::|.|.:....:::|:..||.||.:....::
  Fly   157 GKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVMSKEDGK 221

Human   111 -KDYAFVHM---ERAEDAVEAIRGLDNTEFQGKRMHV---------------------------- 143
             |.:.||..   |.||.||:|:.|.|..|  ||.::|
  Fly   222 SKGFGFVAFETTEAAEAAVQALNGKDMGE--GKSLYVARAQKKAERQQELKRKFEELKQKRHESV 284

Human   144 ------------QLSTSRLR----------TAPGMGDQSG--------CYRCGKEGHWSKECPI- 177
                        .:...|||          :|..|.|:.|        |:....|.    .|.:
  Fly   285 FGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRSKGFGFVCFNAASEA----TCAVT 345

Human   178 DRSGRV------------------ADLTEQYNEQYGAVRTPYTMSYGDSLYYNNA---------- 214
            :.:|||                  |.|..||......:|    |.....:|..||
  Fly   346 ELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMR----MQQLGQIYQPNAASGFFVPTLP 406

Human   215 -----YGALDAYYKR-----------CRAARSYEAVAAAAASVYNYAEQTLSQL----------- 252
                 :|:..|...|           ..|.:..:|.||||......|....:|.
  Fly   407 SNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQGTAGAVPTQFRSAAAGARGAQ 471

Human   253 PQVQNT----AMASHLTSTSLDPYDRHLLPTSGAAA-----TAA-------AAAAAAAAVTAAST 301
            ||||.|    |.|:::.:|             ||.|     |||       |..|..|....::.
  Fly   472 PQVQGTHAAAAAANNMRNT-------------GARAITGQQTAAPNMQIPGAQIAGGAQQRTSNY 523

Human   302 SYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNS 343
            .|....|:|      |||.:       |:::........:||
  Fly   524 KYTSNMRNP------PVPQL-------HQTQPIPQQLQGKNS 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM4	NP_002887.2	RRM1_RBM4	2..68	CDD:410018	23/77 (30%)
		RRM2_RBM4	78..144	CDD:410019	23/115 (20%)
		PTZ00368	<145..>181	CDD:173561	10/54 (19%)
		ZnF_C2HC	161..176	CDD:197667	3/22 (14%)
		Interaction with TNPO3. /evidence=ECO:0000269|PubMed:12628928	196..364		42/201 (21%)
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	109/497 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910