DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBM4 and fne

DIOPT Version :9

Sequence 1:	NP_002887.2	Gene:	RBM4 / 5936	HGNCID:	9901	Length:	364	Species:	Homo sapiens
Sequence 2:	NP_001096965.1	Gene:	fne / 32245	FlyBaseID:	FBgn0086675	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	171	Identity:	38/171 - (22%)
Similarity:	71/171 - (41%)	Gaps:	36/171 - (21%)

- Green bases have known domain annotations that are detailed below.

Human     4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------------------------YGFVHI 42
            |.:..||:..|::|:||||...|::..|.::::                          ||||:.
  Fly    28 LIVNYLPQTMTQEEMRSLFSSIGELESCKLVRDKVSGNLVLPASLTALNPALQQGQSLGYGFVNY 92

Human    43 EDKTAAEDAIRNLHHYKLHGVNINVEASKNKSKT--STKLHVGNISPTCTNKELRAKFEEYGPVI 105
            .....||.|:..|:..:|....|.|..::..|::  ...|:|..:....:..:|...|..:|.:|
  Fly    93 VRAEDAEKAVNTLNGLRLQNKVIKVSYARPSSESIKGANLYVSGLPKNLSQPDLEGMFASFGKII 157

Human   106 E----CD----IVKDYAFVHMERAEDAVEAIRGLDNTEFQG 138
            .    ||    :.|...|:..::..:|..||:.|:....:|
  Fly   158 TSRILCDNISGLSKGVGFIRFDQRNEAERAIQELNGKTPKG 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM4	NP_002887.2	RRM1_RBM4	2..68	CDD:410018	21/89 (24%)
		RRM2_RBM4	78..144	CDD:410019	15/69 (22%)
		PTZ00368	<145..>181	CDD:173561
		ZnF_C2HC	161..176	CDD:197667
		Interaction with TNPO3. /evidence=ECO:0000269\|PubMed:12628928	196..364
fne	NP_001096965.1	ELAV_HUD_SF	23..354	CDD:273741	38/171 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910